1-O-acylceramides are natural components of human and mouse epidermis[S]
The lipid-rich stratum corneum functions as a barrier against pathogens and desiccation inter alia by an unbroken meshwork of extracellular lipid lamellae. These lamellae are composed of cholesterol, fatty acids, and ceramides (Cers) in an equimolar ratio. The huge class of skin Cers consists of thr...
Main Authors: | Mariona Rabionet, Aline Bayerle, Christian Marsching, Richard Jennemann, Hermann-Josef Gröne, Yildiz Yildiz, Dagmar Wachten, Walter Shaw, James A. Shayman, Roger Sandhoff |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-12-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520356844 |
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