Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study

Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study

Abstract Background Recent evidence indicates that ataxia telangiectasia mutated (ATM) is a cytoplasmic protein that involves in insulin signaling pathways. When ATM gene is mutated, this event appears to contribute to the development of insulin resistance and type 2 diabetes mellitus (T2DM). Up to...

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Bibliographic Details
Main Authors: Xiang Ding, Qiukui Hao, Ming Yang, Tie Chen, Shanping Chen, Jirong Yue, Sean X. Leng, Birong Dong
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Medical Genetics
Subjects:
Ataxia telangiectasia mutated
rs189037
Single nucleoside polymorphism
Type 2 diabetes mellitus
Coronary artery disease
Online Access:http://link.springer.com/article/10.1186/s12881-017-0446-z

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