Melatonin Inhibits Formation of Mitochondrial Permeability Transition Pores and Improves Oxidative Phosphorylation of Frozen-Thawed Ram Sperm

Melatonin Inhibits Formation of Mitochondrial Permeability Transition Pores and Improves Oxidative Phosphorylation of Frozen-Thawed Ram Sperm

Structural and functional damages to mitochondria of frozen-thawed sperm are a typical cryoinjury, with mitochondrial permeability transition pore (MPTP) formation being the hallmark change. Mitochondria are both a primary synthesis site and principle target for melatonin; this compound can directly...

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Bibliographic Details
Main Authors: Yi Fang, Chengzhen Zhao, Hai Xiang, Xueli Zhao, Rongzhen Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Endocrinology
Subjects:
ram
sperm
cryopreservation
melatonin
mitochondrial permeability transition pore
oxidative phosphorylation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00896/full

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