SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION

Unique physicochemical properties of nanomaterials arouse a great interest of specialists of various fields. Materials based on nanostructures purchase new mechanical, optical, and electrical properties. Great practical importance is the magnetic properties of materials, structural elements which li...

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Main Authors: G. Yu. Vasyukov, I. V. Mitrofanova, V. V. Ivanova, V. D. Prokopiyeva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2014-12-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/113
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author G. Yu. Vasyukov
I. V. Mitrofanova
V. V. Ivanova
V. D. Prokopiyeva
author_facet G. Yu. Vasyukov
I. V. Mitrofanova
V. V. Ivanova
V. D. Prokopiyeva
author_sort G. Yu. Vasyukov
collection DOAJ
description Unique physicochemical properties of nanomaterials arouse a great interest of specialists of various fields. Materials based on nanostructures purchase new mechanical, optical, and electrical properties. Great practical importance is the magnetic properties of materials, structural elements which lie at the nanoscale. Nanomaterials with magnetic properties have been used in drug delivery, magnetic hyperthermia, magnetic separation, and magnetic resonance imaging. Magnetic properties of nanoparticles depend on many factors, such as particle size and shape, chemical properties and lattice type. Magnetic characteristics can be changed by the interaction of particles with the surrounding matrix and neighboring particles.Unfortunately, many studies show that a great disadvantage of the unmodified nanoparticles is their non-specific interaction with the cells, which leads to their accumulation outside the target organs, also to­xicity of nanomaterials and their low colloidal stability. Surface modification of nanoparticles can solve this problem. Development of nanostructures based on magnetic nanoparticles and functionalized by biocompatible agents is one of the main targets of nanobiotechnology.
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spelling doaj.art-2d67810495dc457696191e8a8944b73f2023-03-13T09:58:20ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842014-12-01136334010.20538/1682-0363-2014-6-33-40111SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATIONG. Yu. Vasyukov0I. V. Mitrofanova1V. V. Ivanova2V. D. Prokopiyeva3Сибирский государственный медицинский университет, Томск; НИИ комплексных проблем сердечно-сосудистых заболеваний СО РАМН, КемеровоСибирский государственный медицинский университет, ТомскСибирский государственный медицинский университет, ТомскНИИ психического здоровья СО РАМН, ТомскUnique physicochemical properties of nanomaterials arouse a great interest of specialists of various fields. Materials based on nanostructures purchase new mechanical, optical, and electrical properties. Great practical importance is the magnetic properties of materials, structural elements which lie at the nanoscale. Nanomaterials with magnetic properties have been used in drug delivery, magnetic hyperthermia, magnetic separation, and magnetic resonance imaging. Magnetic properties of nanoparticles depend on many factors, such as particle size and shape, chemical properties and lattice type. Magnetic characteristics can be changed by the interaction of particles with the surrounding matrix and neighboring particles.Unfortunately, many studies show that a great disadvantage of the unmodified nanoparticles is their non-specific interaction with the cells, which leads to their accumulation outside the target organs, also to­xicity of nanomaterials and their low colloidal stability. Surface modification of nanoparticles can solve this problem. Development of nanostructures based on magnetic nanoparticles and functionalized by biocompatible agents is one of the main targets of nanobiotechnology.https://bulletin.ssmu.ru/jour/article/view/113ультрадисперсные материалымагнитные наночастицыклеточная биологиянанотоксикологияповерхностная модификация
spellingShingle G. Yu. Vasyukov
I. V. Mitrofanova
V. V. Ivanova
V. D. Prokopiyeva
SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION
Бюллетень сибирской медицины
ультрадисперсные материалы
магнитные наночастицы
клеточная биология
нанотоксикология
поверхностная модификация
title SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION
title_full SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION
title_fullStr SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION
title_full_unstemmed SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION
title_short SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION
title_sort surface modifited magnetic nanoparticles for biomedical application
topic ультрадисперсные материалы
магнитные наночастицы
клеточная биология
нанотоксикология
поверхностная модификация
url https://bulletin.ssmu.ru/jour/article/view/113
work_keys_str_mv AT gyuvasyukov surfacemodifitedmagneticnanoparticlesforbiomedicalapplication
AT ivmitrofanova surfacemodifitedmagneticnanoparticlesforbiomedicalapplication
AT vvivanova surfacemodifitedmagneticnanoparticlesforbiomedicalapplication
AT vdprokopiyeva surfacemodifitedmagneticnanoparticlesforbiomedicalapplication