SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION
Unique physicochemical properties of nanomaterials arouse a great interest of specialists of various fields. Materials based on nanostructures purchase new mechanical, optical, and electrical properties. Great practical importance is the magnetic properties of materials, structural elements which li...
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Format: | Article |
Language: | English |
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Siberian State Medical University (Tomsk)
2014-12-01
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Series: | Бюллетень сибирской медицины |
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Online Access: | https://bulletin.ssmu.ru/jour/article/view/113 |
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author | G. Yu. Vasyukov I. V. Mitrofanova V. V. Ivanova V. D. Prokopiyeva |
author_facet | G. Yu. Vasyukov I. V. Mitrofanova V. V. Ivanova V. D. Prokopiyeva |
author_sort | G. Yu. Vasyukov |
collection | DOAJ |
description | Unique physicochemical properties of nanomaterials arouse a great interest of specialists of various fields. Materials based on nanostructures purchase new mechanical, optical, and electrical properties. Great practical importance is the magnetic properties of materials, structural elements which lie at the nanoscale. Nanomaterials with magnetic properties have been used in drug delivery, magnetic hyperthermia, magnetic separation, and magnetic resonance imaging. Magnetic properties of nanoparticles depend on many factors, such as particle size and shape, chemical properties and lattice type. Magnetic characteristics can be changed by the interaction of particles with the surrounding matrix and neighboring particles.Unfortunately, many studies show that a great disadvantage of the unmodified nanoparticles is their non-specific interaction with the cells, which leads to their accumulation outside the target organs, also toxicity of nanomaterials and their low colloidal stability. Surface modification of nanoparticles can solve this problem. Development of nanostructures based on magnetic nanoparticles and functionalized by biocompatible agents is one of the main targets of nanobiotechnology. |
first_indexed | 2024-04-10T01:07:14Z |
format | Article |
id | doaj.art-2d67810495dc457696191e8a8944b73f |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:07:14Z |
publishDate | 2014-12-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-2d67810495dc457696191e8a8944b73f2023-03-13T09:58:20ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842014-12-01136334010.20538/1682-0363-2014-6-33-40111SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATIONG. Yu. Vasyukov0I. V. Mitrofanova1V. V. Ivanova2V. D. Prokopiyeva3Сибирский государственный медицинский университет, Томск; НИИ комплексных проблем сердечно-сосудистых заболеваний СО РАМН, КемеровоСибирский государственный медицинский университет, ТомскСибирский государственный медицинский университет, ТомскНИИ психического здоровья СО РАМН, ТомскUnique physicochemical properties of nanomaterials arouse a great interest of specialists of various fields. Materials based on nanostructures purchase new mechanical, optical, and electrical properties. Great practical importance is the magnetic properties of materials, structural elements which lie at the nanoscale. Nanomaterials with magnetic properties have been used in drug delivery, magnetic hyperthermia, magnetic separation, and magnetic resonance imaging. Magnetic properties of nanoparticles depend on many factors, such as particle size and shape, chemical properties and lattice type. Magnetic characteristics can be changed by the interaction of particles with the surrounding matrix and neighboring particles.Unfortunately, many studies show that a great disadvantage of the unmodified nanoparticles is their non-specific interaction with the cells, which leads to their accumulation outside the target organs, also toxicity of nanomaterials and their low colloidal stability. Surface modification of nanoparticles can solve this problem. Development of nanostructures based on magnetic nanoparticles and functionalized by biocompatible agents is one of the main targets of nanobiotechnology.https://bulletin.ssmu.ru/jour/article/view/113ультрадисперсные материалымагнитные наночастицыклеточная биологиянанотоксикологияповерхностная модификация |
spellingShingle | G. Yu. Vasyukov I. V. Mitrofanova V. V. Ivanova V. D. Prokopiyeva SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION Бюллетень сибирской медицины ультрадисперсные материалы магнитные наночастицы клеточная биология нанотоксикология поверхностная модификация |
title | SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION |
title_full | SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION |
title_fullStr | SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION |
title_full_unstemmed | SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION |
title_short | SURFACE MODIFITED MAGNETIC NANOPARTICLES FOR BIOMEDICAL APPLICATION |
title_sort | surface modifited magnetic nanoparticles for biomedical application |
topic | ультрадисперсные материалы магнитные наночастицы клеточная биология нанотоксикология поверхностная модификация |
url | https://bulletin.ssmu.ru/jour/article/view/113 |
work_keys_str_mv | AT gyuvasyukov surfacemodifitedmagneticnanoparticlesforbiomedicalapplication AT ivmitrofanova surfacemodifitedmagneticnanoparticlesforbiomedicalapplication AT vvivanova surfacemodifitedmagneticnanoparticlesforbiomedicalapplication AT vdprokopiyeva surfacemodifitedmagneticnanoparticlesforbiomedicalapplication |