Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study
Abstract Background Depression and dementia are major public health problems in the UK. Depression in early-stage dementia is very common and significantly reduces quality of life, speeds cognitive decline and increases functional impairment. Mindfulness-Based Cognitive Therapy (MBCT) is an effectiv...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-05-01
|
| Series: | Pilot and Feasibility Studies |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40814-017-0143-x |
| _version_ | 1819021003803590656 |
|---|---|
| author | Elisa Aguirre Josh Stott Georgina Charlesworth Deirdre Noone Jacob Payne Mina Patel Aimee Spector |
| author_facet | Elisa Aguirre Josh Stott Georgina Charlesworth Deirdre Noone Jacob Payne Mina Patel Aimee Spector |
| author_sort | Elisa Aguirre |
| collection | DOAJ |
| description | Abstract Background Depression and dementia are major public health problems in the UK. Depression in early-stage dementia is very common and significantly reduces quality of life, speeds cognitive decline and increases functional impairment. Mindfulness-Based Cognitive Therapy (MBCT) is an effective depression prevention programme, and the National Institute for Clinical Excellence (NICE) has suggested that MBCT is a priority for implementation. Alongside this, there is emerging evidence demonstrating promising results in relation to the benefits of adapted mindfulness interventions for people with dementia, suggesting that it could be beneficial in reducing depressive symptoms and in slowing deterioration in cognitive functions such as sustained attention, distraction inhibition and task switching. Methods The design is a single-blind randomised controlled feasibility trial. Participants with mild to moderate depression and early stages of dementia will be recruited from the participating memory services. Participants will receive either immediate or delayed access to an 8-week MBCT programme. Participants will be assessed by a blind assessor and complete cognitive and mood-related outcome measures before and after the intervention. This feasibility study will test the trial design and assess recruitment, retention, acceptability and adherence, as well as providing preliminary efficacy data. Discussion This study will inform the design and sample size for a future full randomised controlled trial (RCT), which will be carried out to determine the effectiveness of the intervention in reducing depressive symptoms in people with early stages of dementia. Trial registration ClinicalTrials.gov ISRCTN16382776 |
| first_indexed | 2024-12-21T04:00:12Z |
| format | Article |
| id | doaj.art-2d67fbfeaf43467a8b1ec38b20d8f2b2 |
| institution | Directory Open Access Journal |
| issn | 2055-5784 |
| language | English |
| last_indexed | 2024-12-21T04:00:12Z |
| publishDate | 2017-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Pilot and Feasibility Studies |
| spelling | doaj.art-2d67fbfeaf43467a8b1ec38b20d8f2b22022-12-21T19:16:45ZengBMCPilot and Feasibility Studies2055-57842017-05-01311710.1186/s40814-017-0143-xMindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility studyElisa Aguirre0Josh Stott1Georgina Charlesworth2Deirdre Noone3Jacob Payne4Mina Patel5Aimee Spector6Research and Development Department, North East London NHS Foundation Trust, Goodmayes HospitalDepartment of Clinical, Education and Health Psychology, University College LondonResearch and Development Department, North East London NHS Foundation Trust, Goodmayes HospitalDepartment of Clinical, Education and Health Psychology, University College LondonDepartment of Clinical, Education and Health Psychology, University College LondonResearch and Development Department, North East London NHS Foundation Trust, Goodmayes HospitalDepartment of Clinical, Education and Health Psychology, University College LondonAbstract Background Depression and dementia are major public health problems in the UK. Depression in early-stage dementia is very common and significantly reduces quality of life, speeds cognitive decline and increases functional impairment. Mindfulness-Based Cognitive Therapy (MBCT) is an effective depression prevention programme, and the National Institute for Clinical Excellence (NICE) has suggested that MBCT is a priority for implementation. Alongside this, there is emerging evidence demonstrating promising results in relation to the benefits of adapted mindfulness interventions for people with dementia, suggesting that it could be beneficial in reducing depressive symptoms and in slowing deterioration in cognitive functions such as sustained attention, distraction inhibition and task switching. Methods The design is a single-blind randomised controlled feasibility trial. Participants with mild to moderate depression and early stages of dementia will be recruited from the participating memory services. Participants will receive either immediate or delayed access to an 8-week MBCT programme. Participants will be assessed by a blind assessor and complete cognitive and mood-related outcome measures before and after the intervention. This feasibility study will test the trial design and assess recruitment, retention, acceptability and adherence, as well as providing preliminary efficacy data. Discussion This study will inform the design and sample size for a future full randomised controlled trial (RCT), which will be carried out to determine the effectiveness of the intervention in reducing depressive symptoms in people with early stages of dementia. Trial registration ClinicalTrials.gov ISRCTN16382776http://link.springer.com/article/10.1186/s40814-017-0143-xDepressionDementiaAlzheimer’sMBCTFeasibility outcomesRCT |
| spellingShingle | Elisa Aguirre Josh Stott Georgina Charlesworth Deirdre Noone Jacob Payne Mina Patel Aimee Spector Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study Pilot and Feasibility Studies Depression Dementia Alzheimer’s MBCT Feasibility outcomes RCT |
| title | Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study |
| title_full | Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study |
| title_fullStr | Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study |
| title_full_unstemmed | Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study |
| title_short | Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study |
| title_sort | mindfulness based cognitive therapy mbct programme for depression in people with early stages of dementia study protocol for a randomised controlled feasibility study |
| topic | Depression Dementia Alzheimer’s MBCT Feasibility outcomes RCT |
| url | http://link.springer.com/article/10.1186/s40814-017-0143-x |
| work_keys_str_mv | AT elisaaguirre mindfulnessbasedcognitivetherapymbctprogrammefordepressioninpeoplewithearlystagesofdementiastudyprotocolforarandomisedcontrolledfeasibilitystudy AT joshstott mindfulnessbasedcognitivetherapymbctprogrammefordepressioninpeoplewithearlystagesofdementiastudyprotocolforarandomisedcontrolledfeasibilitystudy AT georginacharlesworth mindfulnessbasedcognitivetherapymbctprogrammefordepressioninpeoplewithearlystagesofdementiastudyprotocolforarandomisedcontrolledfeasibilitystudy AT deirdrenoone mindfulnessbasedcognitivetherapymbctprogrammefordepressioninpeoplewithearlystagesofdementiastudyprotocolforarandomisedcontrolledfeasibilitystudy AT jacobpayne mindfulnessbasedcognitivetherapymbctprogrammefordepressioninpeoplewithearlystagesofdementiastudyprotocolforarandomisedcontrolledfeasibilitystudy AT minapatel mindfulnessbasedcognitivetherapymbctprogrammefordepressioninpeoplewithearlystagesofdementiastudyprotocolforarandomisedcontrolledfeasibilitystudy AT aimeespector mindfulnessbasedcognitivetherapymbctprogrammefordepressioninpeoplewithearlystagesofdementiastudyprotocolforarandomisedcontrolledfeasibilitystudy |