Genotypic and allelic variability in CYP19A1 among populations of African and European ancestry.

Genotypic and allelic variability in CYP19A1 among populations of African and European ancestry.

CYP19A1 facilitates the bioconversion of estrogens from androgens. CYP19A1 intron single nucleotide polymorphisms (SNPs) may alter mRNA splicing, resulting in altered CYP19A1 activity, and potentially influencing disease susceptibility. Genetic studies of CYP19A1 SNPs have been well documented in po...

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Bibliographic Details
Main Authors: Athena Starlard-Davenport, Mohammed S Orloff, Ishwori Dhakal, Rosalind B Penney, Susan A Kadlubar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4315570?pdf=render

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