A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel Occlusion
As the majority of large vessel occlusion (LVO) patients are not treated with revascularization therapies or efficiently revascularized, complementary management strategies are needed. In this article we explore the importance of cerebral autoregulation (CA) assessment in the prediction and/or modif...
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| Format: | Article |
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1287873/full |
| _version_ | 1827736246527459328 |
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| author | Faheem G. Sheriff Arghal Ahmad Mehmet E. Inam Rakesh Khatri Alberto Maud Gustavo J. Rodriguez |
| author_facet | Faheem G. Sheriff Arghal Ahmad Mehmet E. Inam Rakesh Khatri Alberto Maud Gustavo J. Rodriguez |
| author_sort | Faheem G. Sheriff |
| collection | DOAJ |
| description | As the majority of large vessel occlusion (LVO) patients are not treated with revascularization therapies or efficiently revascularized, complementary management strategies are needed. In this article we explore the importance of cerebral autoregulation (CA) assessment in the prediction and/or modification of infarct growth and hemorrhagic transformation. In patients with LVO, these are important factors that affect prognosis. A systematic search of the PubMed, EMBASE databases and a targeted Google search was conducted, resulting in the inclusion of 34 relevant articles. There is an agreement that CA is impaired in patients with LVO; several factors have been identified such as time course, revascularization status, laterality, disease subtype and location, some of which may be potentially modifiable and affect outcomes. The personalized CA assessment of these patients suggests potential for better understanding of the inter-individual variability. Further research is needed for the development of more accurate, noninvasive techniques for continuous monitoring and personalized thresholds for CA. |
| first_indexed | 2024-03-11T02:06:03Z |
| format | Article |
| id | doaj.art-2d6a0a47136a49678f81b9c5679a6928 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-03-11T02:06:03Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neurology |
| spelling | doaj.art-2d6a0a47136a49678f81b9c5679a69282023-11-18T11:49:38ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-11-011410.3389/fneur.2023.12878731287873A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel OcclusionFaheem G. Sheriff0Arghal Ahmad1Mehmet E. Inam2Rakesh Khatri3Alberto Maud4Gustavo J. Rodriguez5Department of Neurology, Section of Interventional Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, United StatesZiauddin University, Karachi, Sindh, PakistanUniversity of Texas Health Science Center at Houston, Houston, TX, United StatesDepartment of Neurology, Section of Interventional Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, United StatesDepartment of Neurology, Section of Interventional Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, United StatesDepartment of Neurology, Section of Interventional Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, United StatesAs the majority of large vessel occlusion (LVO) patients are not treated with revascularization therapies or efficiently revascularized, complementary management strategies are needed. In this article we explore the importance of cerebral autoregulation (CA) assessment in the prediction and/or modification of infarct growth and hemorrhagic transformation. In patients with LVO, these are important factors that affect prognosis. A systematic search of the PubMed, EMBASE databases and a targeted Google search was conducted, resulting in the inclusion of 34 relevant articles. There is an agreement that CA is impaired in patients with LVO; several factors have been identified such as time course, revascularization status, laterality, disease subtype and location, some of which may be potentially modifiable and affect outcomes. The personalized CA assessment of these patients suggests potential for better understanding of the inter-individual variability. Further research is needed for the development of more accurate, noninvasive techniques for continuous monitoring and personalized thresholds for CA.https://www.frontiersin.org/articles/10.3389/fneur.2023.1287873/fullcerebral autoregulationlarge vessel occlusionacute ischemic strokemechanical thrombectomycerebral blood flow |
| spellingShingle | Faheem G. Sheriff Arghal Ahmad Mehmet E. Inam Rakesh Khatri Alberto Maud Gustavo J. Rodriguez A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel Occlusion Frontiers in Neurology cerebral autoregulation large vessel occlusion acute ischemic stroke mechanical thrombectomy cerebral blood flow |
| title | A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel Occlusion |
| title_full | A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel Occlusion |
| title_fullStr | A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel Occlusion |
| title_full_unstemmed | A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel Occlusion |
| title_short | A systematic review on the assessment of cerebral autoregulation in patients with Large Vessel Occlusion |
| title_sort | systematic review on the assessment of cerebral autoregulation in patients with large vessel occlusion |
| topic | cerebral autoregulation large vessel occlusion acute ischemic stroke mechanical thrombectomy cerebral blood flow |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1287873/full |
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