Clinical epidemiological characterization and survival in patients under 19 years with leukemia

Introduction: Leukemia is the most frequent cancer in childhood and represents 41 % of all the malignancies in children under 15 years.   Objective: To describe the clinical epidemiological characteristics and survival in children and adolescents with leukemia.  Method:  A descriptive, longitudina...

Full description

Bibliographic Details
Main Authors: Nodalys Querol Betancourt, Margarita Isabel Chávez Isla, Coralia Cristina Leblanch Fernández, Niurbis Jimenez Portuondo
Format: Article
Language:Spanish
Published: Centro Provincial de Información de Ciencias Médicas 2021-01-01
Series:Medisan
Subjects:
Online Access:http://medisan.sld.cu/index.php/san/article/view/3303
_version_ 1818415828506247168
author Nodalys Querol Betancourt
Margarita Isabel Chávez Isla
Coralia Cristina Leblanch Fernández
Niurbis Jimenez Portuondo
author_facet Nodalys Querol Betancourt
Margarita Isabel Chávez Isla
Coralia Cristina Leblanch Fernández
Niurbis Jimenez Portuondo
author_sort Nodalys Querol Betancourt
collection DOAJ
description Introduction: Leukemia is the most frequent cancer in childhood and represents 41 % of all the malignancies in children under 15 years.   Objective: To describe the clinical epidemiological characteristics and survival in children and adolescents with leukemia.  Method:  A descriptive, longitudinal and retrospective study of 82 patients under 19 years, with diagnosis of leukemia was carried out. They were assisted in the Regional Service of Hematology at Dr. Antonio María Béguez César Teaching Southern Children Hospital in Santiago de Cuba, from January, 2014 to December, 2018.   Results: In the case material there was a  prevalence of the 1-4 age group (42.7 %), male sex (59.7 %), mixed race children (48.8 %), acute lymphoid leukemia as morphological variant (73.2 %), as well as the anemic and fever syndrome (97.7 and 86.6 %, respectively).  Complete remission was achieved in 89.0 % of the patients after concluding the first phase of the treatment and 17.1 % presented some type of relapse during their clinical course, where the most affected site was the bone marrow. A global survival of 67.1 % was achieved.   Conclusions: The results of the study are encouraging and do not differ from the world clinical and epidemiological context, taking into account  the non availability of diagnosis means in the province, with advanced technology, for a better stratification of patients.
first_indexed 2024-12-14T11:41:12Z
format Article
id doaj.art-2d6a3c73eb2a4dac99a84de565805b87
institution Directory Open Access Journal
issn 1029-3019
language Spanish
last_indexed 2024-12-14T11:41:12Z
publishDate 2021-01-01
publisher Centro Provincial de Información de Ciencias Médicas
record_format Article
series Medisan
spelling doaj.art-2d6a3c73eb2a4dac99a84de565805b872022-12-21T23:02:49ZspaCentro Provincial de Información de Ciencias MédicasMedisan1029-30192021-01-0125126401014Clinical epidemiological characterization and survival in patients under 19 years with leukemiaNodalys Querol Betancourt0Margarita Isabel Chávez Isla1Coralia Cristina Leblanch Fernández2Niurbis Jimenez Portuondo3Hospital Infantil Sur Docente Dr. Antonio María Béguez César, Universidad de Ciencias Médicas. Santiago de CubaHospital Infantil Sur Docente Dr. Antonio María Béguez César, Universidad de Ciencias Médicas. Santiago de CubaHospital Infantil Sur Docente Dr. Antonio María Béguez César, Universidad de Ciencias Médicas. Santiago de CubaHospital Infantil Sur Docente Dr. Antonio María Béguez César, Universidad de Ciencias Médicas. Santiago de CubaIntroduction: Leukemia is the most frequent cancer in childhood and represents 41 % of all the malignancies in children under 15 years.   Objective: To describe the clinical epidemiological characteristics and survival in children and adolescents with leukemia.  Method:  A descriptive, longitudinal and retrospective study of 82 patients under 19 years, with diagnosis of leukemia was carried out. They were assisted in the Regional Service of Hematology at Dr. Antonio María Béguez César Teaching Southern Children Hospital in Santiago de Cuba, from January, 2014 to December, 2018.   Results: In the case material there was a  prevalence of the 1-4 age group (42.7 %), male sex (59.7 %), mixed race children (48.8 %), acute lymphoid leukemia as morphological variant (73.2 %), as well as the anemic and fever syndrome (97.7 and 86.6 %, respectively).  Complete remission was achieved in 89.0 % of the patients after concluding the first phase of the treatment and 17.1 % presented some type of relapse during their clinical course, where the most affected site was the bone marrow. A global survival of 67.1 % was achieved.   Conclusions: The results of the study are encouraging and do not differ from the world clinical and epidemiological context, taking into account  the non availability of diagnosis means in the province, with advanced technology, for a better stratification of patients.http://medisan.sld.cu/index.php/san/article/view/3303niñoadolescenteleucemiaenfermedad malignasupervivenciahospital pediátricoatención secundaria de salud.
spellingShingle Nodalys Querol Betancourt
Margarita Isabel Chávez Isla
Coralia Cristina Leblanch Fernández
Niurbis Jimenez Portuondo
Clinical epidemiological characterization and survival in patients under 19 years with leukemia
Medisan
niño
adolescente
leucemia
enfermedad maligna
supervivencia
hospital pediátrico
atención secundaria de salud.
title Clinical epidemiological characterization and survival in patients under 19 years with leukemia
title_full Clinical epidemiological characterization and survival in patients under 19 years with leukemia
title_fullStr Clinical epidemiological characterization and survival in patients under 19 years with leukemia
title_full_unstemmed Clinical epidemiological characterization and survival in patients under 19 years with leukemia
title_short Clinical epidemiological characterization and survival in patients under 19 years with leukemia
title_sort clinical epidemiological characterization and survival in patients under 19 years with leukemia
topic niño
adolescente
leucemia
enfermedad maligna
supervivencia
hospital pediátrico
atención secundaria de salud.
url http://medisan.sld.cu/index.php/san/article/view/3303
work_keys_str_mv AT nodalysquerolbetancourt clinicalepidemiologicalcharacterizationandsurvivalinpatientsunder19yearswithleukemia
AT margaritaisabelchavezisla clinicalepidemiologicalcharacterizationandsurvivalinpatientsunder19yearswithleukemia
AT coraliacristinaleblanchfernandez clinicalepidemiologicalcharacterizationandsurvivalinpatientsunder19yearswithleukemia
AT niurbisjimenezportuondo clinicalepidemiologicalcharacterizationandsurvivalinpatientsunder19yearswithleukemia