A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants

Bone replacement implants for craniofacial reconstruction require to provide an adequate structural foundation to withstand the physiological loading. With recent advances in 3D printing technology in place of bone grafts using autologous tissues, patient-specific additively manufactured implants ar...

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Main Authors: Jaejong Park, Tareq Zobaer, Alok Sutradhar
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/12/2/101
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author Jaejong Park
Tareq Zobaer
Alok Sutradhar
author_facet Jaejong Park
Tareq Zobaer
Alok Sutradhar
author_sort Jaejong Park
collection DOAJ
description Bone replacement implants for craniofacial reconstruction require to provide an adequate structural foundation to withstand the physiological loading. With recent advances in 3D printing technology in place of bone grafts using autologous tissues, patient-specific additively manufactured implants are being established as suitable alternates. Since the stress distribution of these structures is complicated, efficient design techniques, such as topology optimization, can deliver optimized designs with enhanced functionality. In this work, a two-scale topology optimization approach is proposed that provides multi-material designs for both macrostructures and microstructures. In the first stage, a multi-resolution topology optimization approach is used to produce multi-material designs with maximum stiffness. Then, a microstructure with a desired property supplants the solid domain. This is beneficial for bone implant design since, in addition to imparting the desired functional property to the design, it also introduces porosity. To show the efficacy of the technique, four different large craniofacial defects due to maxillectomy are considered, and their respective implant designs with multi-materials are shown. These designs show good potential in developing patient-specific optimized designs suitable for additive manufacturing.
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spelling doaj.art-2d6be40a28be41df88b387e34273b6122023-12-03T14:02:27ZengMDPI AGMicromachines2072-666X2021-01-0112210110.3390/mi12020101A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone ImplantsJaejong Park0Tareq Zobaer1Alok Sutradhar2Department of Mechanical Engineering, Prairie View A&M University, Prairie View, TX 77446, USADepartment of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USADepartment of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USABone replacement implants for craniofacial reconstruction require to provide an adequate structural foundation to withstand the physiological loading. With recent advances in 3D printing technology in place of bone grafts using autologous tissues, patient-specific additively manufactured implants are being established as suitable alternates. Since the stress distribution of these structures is complicated, efficient design techniques, such as topology optimization, can deliver optimized designs with enhanced functionality. In this work, a two-scale topology optimization approach is proposed that provides multi-material designs for both macrostructures and microstructures. In the first stage, a multi-resolution topology optimization approach is used to produce multi-material designs with maximum stiffness. Then, a microstructure with a desired property supplants the solid domain. This is beneficial for bone implant design since, in addition to imparting the desired functional property to the design, it also introduces porosity. To show the efficacy of the technique, four different large craniofacial defects due to maxillectomy are considered, and their respective implant designs with multi-materials are shown. These designs show good potential in developing patient-specific optimized designs suitable for additive manufacturing.https://www.mdpi.com/2072-666X/12/2/101topology optimizationcraniofacial surgerybone replacementsmulti-materialbone implants
spellingShingle Jaejong Park
Tareq Zobaer
Alok Sutradhar
A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants
Micromachines
topology optimization
craniofacial surgery
bone replacements
multi-material
bone implants
title A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants
title_full A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants
title_fullStr A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants
title_full_unstemmed A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants
title_short A Two-Scale Multi-Resolution Topologically Optimized Multi-Material Design of 3D Printed Craniofacial Bone Implants
title_sort two scale multi resolution topologically optimized multi material design of 3d printed craniofacial bone implants
topic topology optimization
craniofacial surgery
bone replacements
multi-material
bone implants
url https://www.mdpi.com/2072-666X/12/2/101
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