Generation of an inducible RPE-specific Cre transgenic-mouse line.

Generation of an inducible RPE-specific Cre transgenic-mouse line.

The retinal pigment epithelium (RPE) is an epithelial monolayer in the back of the vertebrate eye. RPE dysfunction is associated with retinal degeneration and blindness. In order to fully understand how dysregulation affects visual function, RPE-specific gene knockouts are indispensable. Since the c...

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Bibliographic Details
Main Authors: Sandra Schneider, Nathan Hotaling, Maria Campos, Sarita Rani Patnaik, Kapil Bharti, Helen Louise May-Simera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6237357?pdf=render

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