Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health

Abstract Trabecular bone score (TBS) is a grayscale textural assessment resulting from a computed evaluation of pixel gray-level variations in previously obtained lumbar spine DXA images. It is an index of bone microarchitecture correlated with parameters of bone strength. Higher values of TBS indic...

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Main Authors: Yasser El Miedany, Walaa Elwakil, Mohammed Hassan Abu-Zaid, Safaa Mahran
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:Egyptian Rheumatology and Rehabilitation
Subjects:
Online Access:https://doi.org/10.1186/s43166-024-00252-x
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author Yasser El Miedany
Walaa Elwakil
Mohammed Hassan Abu-Zaid
Safaa Mahran
author_facet Yasser El Miedany
Walaa Elwakil
Mohammed Hassan Abu-Zaid
Safaa Mahran
author_sort Yasser El Miedany
collection DOAJ
description Abstract Trabecular bone score (TBS) is a grayscale textural assessment resulting from a computed evaluation of pixel gray-level variations in previously obtained lumbar spine DXA images. It is an index of bone microarchitecture correlated with parameters of bone strength. Higher values of TBS indicate a better microarchitecture, whereas lower values indicate a degraded microarchitecture. TBS can be used alongside Fracture Risk Assessment tool “FRAX” and bone mineral density (BMD) to enhance the assessment of fracture risk and to inform treatment initiation and monitoring. A systematic review was carried out aiming to update the evidence on the clinical use of the TBS in the management of both primary and secondary osteoporosis. Results revealed that in both primary and secondary osteoporosis, TBS enhances the prediction of fracture risk, and when adjust with BMD and clinical risk factors, it is able to inform the decision-making process regarding initiating osteoporosis therapy and the choice of anti-osteoporosis medication. Evidence also implies that TBS provides valuable adjunctive information in monitoring osteoporosis therapy. In conclusion, this work provides an up-to-date evidence-based review and recommendations which informs the utility of trabecular bone score in standard clinical practice.
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spelling doaj.art-2d70ae881a5d414685fe5882619143452024-03-31T11:22:56ZengSpringerOpenEgyptian Rheumatology and Rehabilitation2090-32352024-03-0151111910.1186/s43166-024-00252-xUpdate on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle HealthYasser El Miedany0Walaa Elwakil1Mohammed Hassan Abu-Zaid2Safaa Mahran3Canterbury Christ Church UniversityPhysical Medicine, Rheumatology and Rehabilitation, Alexandria UniversityRheumatology and Rehabilitation, Tanta UniversityPhysical Medicine, Rheumatology and Rehabilitation, Assiut UniversityAbstract Trabecular bone score (TBS) is a grayscale textural assessment resulting from a computed evaluation of pixel gray-level variations in previously obtained lumbar spine DXA images. It is an index of bone microarchitecture correlated with parameters of bone strength. Higher values of TBS indicate a better microarchitecture, whereas lower values indicate a degraded microarchitecture. TBS can be used alongside Fracture Risk Assessment tool “FRAX” and bone mineral density (BMD) to enhance the assessment of fracture risk and to inform treatment initiation and monitoring. A systematic review was carried out aiming to update the evidence on the clinical use of the TBS in the management of both primary and secondary osteoporosis. Results revealed that in both primary and secondary osteoporosis, TBS enhances the prediction of fracture risk, and when adjust with BMD and clinical risk factors, it is able to inform the decision-making process regarding initiating osteoporosis therapy and the choice of anti-osteoporosis medication. Evidence also implies that TBS provides valuable adjunctive information in monitoring osteoporosis therapy. In conclusion, this work provides an up-to-date evidence-based review and recommendations which informs the utility of trabecular bone score in standard clinical practice.https://doi.org/10.1186/s43166-024-00252-xTrabecular bone scoreTBSDXABMDBone mineral densityOsteoporosis
spellingShingle Yasser El Miedany
Walaa Elwakil
Mohammed Hassan Abu-Zaid
Safaa Mahran
Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health
Egyptian Rheumatology and Rehabilitation
Trabecular bone score
TBS
DXA
BMD
Bone mineral density
Osteoporosis
title Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health
title_full Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health
title_fullStr Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health
title_full_unstemmed Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health
title_short Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health
title_sort update on the utility of trabecular bone score tbs in clinical practice for the management of osteoporosis a systematic review by the egyptian academy of bone and muscle health
topic Trabecular bone score
TBS
DXA
BMD
Bone mineral density
Osteoporosis
url https://doi.org/10.1186/s43166-024-00252-x
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