Apoptotic caspases cut down the immunogenicity of radiation
Caspases are known for their ability to precipitate apoptosis. Our findings indicate that accelerating the terminal inactivation of cells dying in response to radiation therapy limit their immunogenicity as a consequence of reduced type I interferon secretion. Thus, caspase inhibitors stand out as p...
Main Authors: | Aitziber Buqué, Maria Esperanza Rodriguez-Ruiz, Jitka Fucikova, Lorenzo Galluzzi |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2019-11-01
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Series: | OncoImmunology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/2162402X.2019.1655364 |
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