Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital
Introduction: Vitamin D has been implicated to play a very important role in different types of cancers due to its pleotropic effects such as cell proliferation, cell differentiation, apoptosis etc. The implications of vitamin D deficiency are more evident in breast, prostate and colorectal cancer....
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2017-10-01
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| Series: | National Journal of Laboratory Medicine |
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| Online Access: | http://www.njlm.net/articles/PDF/2256/31900_CE(VSU)_F(GG)_PF1(VSU_GG)_PFA(GG)_PF2(VSU_GG).pdf |
| _version_ | 1818609000595324928 |
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| author | MN Suma Swetha NK Parveen Doddamani Binay Kumar Yadav Akash R |
| author_facet | MN Suma Swetha NK Parveen Doddamani Binay Kumar Yadav Akash R |
| author_sort | MN Suma |
| collection | DOAJ |
| description | Introduction: Vitamin D has been implicated to play a very important role in different types of cancers due to its pleotropic effects such as cell proliferation, cell differentiation, apoptosis etc. The implications of vitamin D deficiency are more evident in breast, prostate and colorectal cancer. Studies have revealed vitamin D supplementation reduces the risk of Breast cancer.
Aim: The main objective of our study was to find out whether low serum 25-hydroxy vitamin D levels was associated with breast cancer.
Materials and Methods: Study group included 25 diagnosed cases of breast cancer. Equal number of age and sex matched healthy persons were included in the control group. Serum 25-hydroxy vitamin D was estimated by electrochemiluminiscence immunoassay.
Results: Mean vitamin D levels were low in breast cancer patients, when compared to controls (p-value < 0.05),which shows that low vitamin D levels are associated with increased risk of breast cancer.
Conclusion: Our study showed that low levels of vitamin D are associated with breast cancer when compared to apparently healthy controls. Estimation of serum vitamin D in patients with breast cancer might help in the early diagnosis and treatment of breast cancer. |
| first_indexed | 2024-12-16T14:51:35Z |
| format | Article |
| id | doaj.art-2d73776e1cea4b1e9d3fdd778978297d |
| institution | Directory Open Access Journal |
| issn | 2277-8551 2455-6882 |
| language | English |
| last_indexed | 2024-12-16T14:51:35Z |
| publishDate | 2017-10-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-2d73776e1cea4b1e9d3fdd778978297d2022-12-21T22:27:35ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822017-10-0164BO22BO2410.7860/NJLM/2017/31900:2256Evaluation of Vitamin D in Breast Cancer in a Tertiary Care HospitalMN Suma0Swetha NK1Parveen Doddamani2Binay Kumar Yadav3Akash R4Professor, Department of Biochemistry, JSS Medical College, Mysuru, Karnataka, India.Assistant Professor, Department of Biochemistry, JSS Medical College, Mysuru, Karnataka, India.Consultant Biochemist, Department of Clinical Biochemistry, JSS Hospital, Mysuru, Karnataka, India.Postgraduate, Department of Biochemistry, JSS Medical College, Mysuru, Karnataka, India.Postgraduate, Department of Biochemistry, JSS Medical College, Mysuru, Karnataka, India.Introduction: Vitamin D has been implicated to play a very important role in different types of cancers due to its pleotropic effects such as cell proliferation, cell differentiation, apoptosis etc. The implications of vitamin D deficiency are more evident in breast, prostate and colorectal cancer. Studies have revealed vitamin D supplementation reduces the risk of Breast cancer. Aim: The main objective of our study was to find out whether low serum 25-hydroxy vitamin D levels was associated with breast cancer. Materials and Methods: Study group included 25 diagnosed cases of breast cancer. Equal number of age and sex matched healthy persons were included in the control group. Serum 25-hydroxy vitamin D was estimated by electrochemiluminiscence immunoassay. Results: Mean vitamin D levels were low in breast cancer patients, when compared to controls (p-value < 0.05),which shows that low vitamin D levels are associated with increased risk of breast cancer. Conclusion: Our study showed that low levels of vitamin D are associated with breast cancer when compared to apparently healthy controls. Estimation of serum vitamin D in patients with breast cancer might help in the early diagnosis and treatment of breast cancer.http://www.njlm.net/articles/PDF/2256/31900_CE(VSU)_F(GG)_PF1(VSU_GG)_PFA(GG)_PF2(VSU_GG).pdfColorectal cancerSupplementationVitamin D deficiency |
| spellingShingle | MN Suma Swetha NK Parveen Doddamani Binay Kumar Yadav Akash R Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital National Journal of Laboratory Medicine Colorectal cancer Supplementation Vitamin D deficiency |
| title | Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital |
| title_full | Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital |
| title_fullStr | Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital |
| title_full_unstemmed | Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital |
| title_short | Evaluation of Vitamin D in Breast Cancer in a Tertiary Care Hospital |
| title_sort | evaluation of vitamin d in breast cancer in a tertiary care hospital |
| topic | Colorectal cancer Supplementation Vitamin D deficiency |
| url | http://www.njlm.net/articles/PDF/2256/31900_CE(VSU)_F(GG)_PF1(VSU_GG)_PFA(GG)_PF2(VSU_GG).pdf |
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