Synthesis, glycosidase inhibitory activity and computational studies of dideoxymethylnojirimycin and its derivatives
We report here the synthesis and biological evaluation of dideoxynojirimycin and its analogs and their functional effect on glucosidase enzyme inhibition against α-glucosidase(yeast), α-galactosidase and β-galactosidase (kluyveromyces lactis). All the compounds significantly inhibited the α-glucosid...
Main Authors: | Jattuboyina Siva Krishna, Hanumantharayappa Bharathkumar, Saikumar Nalla, Sahadev S Chirke, Shalini Basetty, Vyshnavi Racha, Thenkrishnan Kumaraguru, Ramars Amanchy, Batchu Venkateswara Rao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715623002540 |
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