Prevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast Ethiopia
Abstract Background Chronic kidney disease (CKD) is a serious complication of diabetes associated with adverse outcomes of renal failure, cardiovascular disease and mortality. Despite this, data regarding the burden and awareness of CKD among adults with diabetes in Sub-Saharan Africa countries are...
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| Format: | Article |
| Language: | English |
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BMC
2020-04-01
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| Series: | BMC Nephrology |
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| Online Access: | http://link.springer.com/article/10.1186/s12882-020-01768-y |
| _version_ | 1819052069637586944 |
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| author | Temesgen Fiseha Zemenu Tamir |
| author_facet | Temesgen Fiseha Zemenu Tamir |
| author_sort | Temesgen Fiseha |
| collection | DOAJ |
| description | Abstract Background Chronic kidney disease (CKD) is a serious complication of diabetes associated with adverse outcomes of renal failure, cardiovascular disease and mortality. Despite this, data regarding the burden and awareness of CKD among adults with diabetes in Sub-Saharan Africa countries are lacking. The aim of this study was, therefore to determine the prevalence and awareness of CKD among diabetic outpatients attending a hospital in Northeast Ethiopia. Methods We conducted a cross-sectional study on 323 diabetic adults at the diabetes clinic of a hospital in Northeast Ethiopia, from February 1 to July 30, 2016. Each patient provided a blood sample for serum creatinine and urine for albuminuria. Glomerular filtration rate (eGFR) was estimated using the Modification of Diet in Renal Disease (MDRD) equation. CKD was defined as eGFR < 60 ml/min/1.73 m2 and/or albuminuria. Awareness was defined as a positive response to “Has a doctor or other health care professional ever told you that you had kidney disease?” Results Of the 323 patients, 85 (26.3%) had Stage 1–5 CKD, 42 (13.0%) had eGFR < 60 ml/min/1.73m2 and 58 (18.0%) had albuminuria. In patients with eGFR < 60 ml/min/1.73m2 (stage 3–5 CKD), serum creatinine was abnormal (> 1.5 mg/dl) in 23.5% and albuminuria was absent in 31.8%. Of the patients with CKD, only 10.6% of them were aware of their CKD. The proportion of patients who were aware of their disease increased with worsening of CKD stages, from 3.4% of with stage 1 to 75.0% with stage 4. Awareness for all individuals with advanced stages of CKD was only 11.9%. Having albuminuria, high serum creatinine, a family history of kidney disease and being obese were significantly associated with CKD awareness. Conclusion A high prevalence but low awareness of CKD was found in diabetic outpatients attending our clinic in Northeast Ethiopia. Our results highlight the need for more diagnostic strategies for CKD screening among diabetic adults and primary care education on the impact of detecting CKD in the early stage to prevent adverse outcomes and improve diabetes care. |
| first_indexed | 2024-12-21T12:13:58Z |
| format | Article |
| id | doaj.art-2d7635b80c764e25be63f12aeceef1a1 |
| institution | Directory Open Access Journal |
| issn | 1471-2369 |
| language | English |
| last_indexed | 2024-12-21T12:13:58Z |
| publishDate | 2020-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Nephrology |
| spelling | doaj.art-2d7635b80c764e25be63f12aeceef1a12022-12-21T19:04:30ZengBMCBMC Nephrology1471-23692020-04-012111710.1186/s12882-020-01768-yPrevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast EthiopiaTemesgen Fiseha0Zemenu Tamir1Department of Clinical Laboratory Science, College of Medicine and Health Sciences, Wollo UniversityDepartment of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa UniversityAbstract Background Chronic kidney disease (CKD) is a serious complication of diabetes associated with adverse outcomes of renal failure, cardiovascular disease and mortality. Despite this, data regarding the burden and awareness of CKD among adults with diabetes in Sub-Saharan Africa countries are lacking. The aim of this study was, therefore to determine the prevalence and awareness of CKD among diabetic outpatients attending a hospital in Northeast Ethiopia. Methods We conducted a cross-sectional study on 323 diabetic adults at the diabetes clinic of a hospital in Northeast Ethiopia, from February 1 to July 30, 2016. Each patient provided a blood sample for serum creatinine and urine for albuminuria. Glomerular filtration rate (eGFR) was estimated using the Modification of Diet in Renal Disease (MDRD) equation. CKD was defined as eGFR < 60 ml/min/1.73 m2 and/or albuminuria. Awareness was defined as a positive response to “Has a doctor or other health care professional ever told you that you had kidney disease?” Results Of the 323 patients, 85 (26.3%) had Stage 1–5 CKD, 42 (13.0%) had eGFR < 60 ml/min/1.73m2 and 58 (18.0%) had albuminuria. In patients with eGFR < 60 ml/min/1.73m2 (stage 3–5 CKD), serum creatinine was abnormal (> 1.5 mg/dl) in 23.5% and albuminuria was absent in 31.8%. Of the patients with CKD, only 10.6% of them were aware of their CKD. The proportion of patients who were aware of their disease increased with worsening of CKD stages, from 3.4% of with stage 1 to 75.0% with stage 4. Awareness for all individuals with advanced stages of CKD was only 11.9%. Having albuminuria, high serum creatinine, a family history of kidney disease and being obese were significantly associated with CKD awareness. Conclusion A high prevalence but low awareness of CKD was found in diabetic outpatients attending our clinic in Northeast Ethiopia. Our results highlight the need for more diagnostic strategies for CKD screening among diabetic adults and primary care education on the impact of detecting CKD in the early stage to prevent adverse outcomes and improve diabetes care.http://link.springer.com/article/10.1186/s12882-020-01768-yChronic kidney diseaseCKD awarenessEstimated glomerular filtration rateDiabetes |
| spellingShingle | Temesgen Fiseha Zemenu Tamir Prevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast Ethiopia BMC Nephrology Chronic kidney disease CKD awareness Estimated glomerular filtration rate Diabetes |
| title | Prevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast Ethiopia |
| title_full | Prevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast Ethiopia |
| title_fullStr | Prevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast Ethiopia |
| title_full_unstemmed | Prevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast Ethiopia |
| title_short | Prevalence and awareness of chronic kidney disease among adult diabetic outpatients in Northeast Ethiopia |
| title_sort | prevalence and awareness of chronic kidney disease among adult diabetic outpatients in northeast ethiopia |
| topic | Chronic kidney disease CKD awareness Estimated glomerular filtration rate Diabetes |
| url | http://link.springer.com/article/10.1186/s12882-020-01768-y |
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