COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?

Arterial hypertension (AH) and obesity are the main risk factors of chronic noncommunicable diseases. Adipous tissue is not only a depot for energetic compounds, but is an active endocrine organ synthetizing biologically active substances that facilitate development of AH. Patients with AH and obesi...

Full description

Bibliographic Details
Main Authors: Yu. A. Vasyuk, E. Yu. Shupenina, E. A. Nesterova, E. I. Golubkova, V. V. Nesvetov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2017-10-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2512
_version_ 1797856871813480448
author Yu. A. Vasyuk
E. Yu. Shupenina
E. A. Nesterova
E. I. Golubkova
V. V. Nesvetov
author_facet Yu. A. Vasyuk
E. Yu. Shupenina
E. A. Nesterova
E. I. Golubkova
V. V. Nesvetov
author_sort Yu. A. Vasyuk
collection DOAJ
description Arterial hypertension (AH) and obesity are the main risk factors of chronic noncommunicable diseases. Adipous tissue is not only a depot for energetic compounds, but is an active endocrine organ synthetizing biologically active substances that facilitate development of AH. Patients with AH and obesity are in the high cardiovascular risk group and demand effective combination antihypertension therapy. One of such drugs is the fixed combination of azilsartan medoxomil and chlorthalidone, which safety and efficacy are confirmed by various trials. Our clinical case demonstrates positive action of Edarbi Сlo on office and 24-hour blood pressure (BP), main parameters of aorta stiffness and structural and functional condition of myocardium at rest, as in exertion in patient with AH and obesity.
first_indexed 2024-04-09T20:47:33Z
format Article
id doaj.art-2d779ec42ccb4807af0f3256ed62d5b4
institution Directory Open Access Journal
issn 1560-4071
2618-7620
language Russian
last_indexed 2024-04-09T20:47:33Z
publishDate 2017-10-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj.art-2d779ec42ccb4807af0f3256ed62d5b42023-03-29T21:23:28Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202017-10-010810210610.15829/1560-4071-2017-8-102-1062246COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?Yu. A. Vasyuk0E. Yu. Shupenina1E. A. Nesterova2E. I. Golubkova3V. V. Nesvetov4A. I. Evdokimov Moscow State University of Medicine and Dentistry (MSUMD)A. I. Evdokimov Moscow State University of Medicine and Dentistry (MSUMD)A. I. Evdokimov Moscow State University of Medicine and Dentistry (MSUMD)A. I. Evdokimov Moscow State University of Medicine and Dentistry (MSUMD)A. I. Evdokimov Moscow State University of Medicine and Dentistry (MSUMD)Arterial hypertension (AH) and obesity are the main risk factors of chronic noncommunicable diseases. Adipous tissue is not only a depot for energetic compounds, but is an active endocrine organ synthetizing biologically active substances that facilitate development of AH. Patients with AH and obesity are in the high cardiovascular risk group and demand effective combination antihypertension therapy. One of such drugs is the fixed combination of azilsartan medoxomil and chlorthalidone, which safety and efficacy are confirmed by various trials. Our clinical case demonstrates positive action of Edarbi Сlo on office and 24-hour blood pressure (BP), main parameters of aorta stiffness and structural and functional condition of myocardium at rest, as in exertion in patient with AH and obesity.https://russjcardiol.elpub.ru/jour/article/view/2512arterial hypertensionobesityaortic stiffnessdiastolic dysfunctionexercise tolerance
spellingShingle Yu. A. Vasyuk
E. Yu. Shupenina
E. A. Nesterova
E. I. Golubkova
V. V. Nesvetov
COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?
Российский кардиологический журнал
arterial hypertension
obesity
aortic stiffness
diastolic dysfunction
exercise tolerance
title COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?
title_full COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?
title_fullStr COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?
title_full_unstemmed COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?
title_short COMBINATION OF AZILSARTAN MEDOXOMIL AND CHLORTHALIDONE: IS IT POSSIBLE TO FIGHT SYSTEMIC HYPERTENSION AND OBESITY TOGETHER?
title_sort combination of azilsartan medoxomil and chlorthalidone is it possible to fight systemic hypertension and obesity together
topic arterial hypertension
obesity
aortic stiffness
diastolic dysfunction
exercise tolerance
url https://russjcardiol.elpub.ru/jour/article/view/2512
work_keys_str_mv AT yuavasyuk combinationofazilsartanmedoxomilandchlorthalidoneisitpossibletofightsystemichypertensionandobesitytogether
AT eyushupenina combinationofazilsartanmedoxomilandchlorthalidoneisitpossibletofightsystemichypertensionandobesitytogether
AT eanesterova combinationofazilsartanmedoxomilandchlorthalidoneisitpossibletofightsystemichypertensionandobesitytogether
AT eigolubkova combinationofazilsartanmedoxomilandchlorthalidoneisitpossibletofightsystemichypertensionandobesitytogether
AT vvnesvetov combinationofazilsartanmedoxomilandchlorthalidoneisitpossibletofightsystemichypertensionandobesitytogether