Intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case report
Abstract Background Polycythemia vera (PV) is a myeloproliferative neoplasm with increased hemoglobin, hematocrit, platelet count and leukocytosis, resulting in increased blood viscosity. PV which is initially presenting with ocular symptoms is rare, but irreversible retinal vessel occlusions leadin...
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02423-w |
| _version_ | 1811235400698560512 |
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| author | Jasmin Regensburger Teresa Rauchegger Lorin Loacker Florian Falkner Clemens Feistritzer Barbara Teuchner |
| author_facet | Jasmin Regensburger Teresa Rauchegger Lorin Loacker Florian Falkner Clemens Feistritzer Barbara Teuchner |
| author_sort | Jasmin Regensburger |
| collection | DOAJ |
| description | Abstract Background Polycythemia vera (PV) is a myeloproliferative neoplasm with increased hemoglobin, hematocrit, platelet count and leukocytosis, resulting in increased blood viscosity. PV which is initially presenting with ocular symptoms is rare, but irreversible retinal vessel occlusions leading to the diagnosis of PV have been described in literature. Case presentation We describe a patient with PV, initially presenting with attacks of monocular temporary loss of vision due to intermittent retinal artery occlusions of different retinal arteries. The patient was immediately treated with phlebotomy and the impaired arterial retinal perfusion could be restored without permanent retinal ischemia. We were able to document these transient arterial occlusions with fundus photography as well as fluorescein angiography. To the best of our knowledge, a case like this has never been documented before. Conclusion This report is pertinent, in order to raise awareness among clinicians for polycythemia vera, as it can in fact be used as a differential diagnosis for patients with retinal artery occlusion. We would like to stress that early therapy might reverse the vessel complications. |
| first_indexed | 2024-04-12T11:50:24Z |
| format | Article |
| id | doaj.art-2d7ca5e775f24d2ebca520c76c34c3e3 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-04-12T11:50:24Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-2d7ca5e775f24d2ebca520c76c34c3e32022-12-22T03:34:11ZengBMCBMC Ophthalmology1471-24152022-05-012211610.1186/s12886-022-02423-wIntermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case reportJasmin Regensburger0Teresa Rauchegger1Lorin Loacker2Florian Falkner3Clemens Feistritzer4Barbara Teuchner5Department of Ophthalmology and Optometry, Medical University InnsbruckDepartment of Ophthalmology and Optometry, Medical University InnsbruckCentral Institute for Medical and Chemical Laboratory Diagnostics, Medical University of InnsbruckTyrolpath Obrist Brunhuber GmbHDepartment of Internal Medicine, Medical University InnsbruckDepartment of Ophthalmology and Optometry, Medical University InnsbruckAbstract Background Polycythemia vera (PV) is a myeloproliferative neoplasm with increased hemoglobin, hematocrit, platelet count and leukocytosis, resulting in increased blood viscosity. PV which is initially presenting with ocular symptoms is rare, but irreversible retinal vessel occlusions leading to the diagnosis of PV have been described in literature. Case presentation We describe a patient with PV, initially presenting with attacks of monocular temporary loss of vision due to intermittent retinal artery occlusions of different retinal arteries. The patient was immediately treated with phlebotomy and the impaired arterial retinal perfusion could be restored without permanent retinal ischemia. We were able to document these transient arterial occlusions with fundus photography as well as fluorescein angiography. To the best of our knowledge, a case like this has never been documented before. Conclusion This report is pertinent, in order to raise awareness among clinicians for polycythemia vera, as it can in fact be used as a differential diagnosis for patients with retinal artery occlusion. We would like to stress that early therapy might reverse the vessel complications.https://doi.org/10.1186/s12886-022-02423-wIntermittent retinal artery occlusionPolycythemia veraMyeloproliferative neoplasmJAK2-V617F mutationFluorescence angiographyCase report |
| spellingShingle | Jasmin Regensburger Teresa Rauchegger Lorin Loacker Florian Falkner Clemens Feistritzer Barbara Teuchner Intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case report BMC Ophthalmology Intermittent retinal artery occlusion Polycythemia vera Myeloproliferative neoplasm JAK2-V617F mutation Fluorescence angiography Case report |
| title | Intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case report |
| title_full | Intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case report |
| title_fullStr | Intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case report |
| title_full_unstemmed | Intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case report |
| title_short | Intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera: a case report |
| title_sort | intermittent retinal artery occlusions as the first clinical manifestation of polycythemia vera a case report |
| topic | Intermittent retinal artery occlusion Polycythemia vera Myeloproliferative neoplasm JAK2-V617F mutation Fluorescence angiography Case report |
| url | https://doi.org/10.1186/s12886-022-02423-w |
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