Förster resonance energy transfer biosensors for fluorescence and time-gated luminescence analysis of rac1 activity

Förster resonance energy transfer biosensors for fluorescence and time-gated luminescence analysis of rac1 activity

Abstract Genetically encoded, Förster resonance energy transfer (FRET) biosensors enable live-cell optical imaging of signaling molecules. Small conformational changes often limit the dynamic range of biosensors that combine fluorescent proteins (FPs) and sensing domains into a single polypeptide. T...

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Bibliographic Details
Main Authors: Ha Pham, Mona Hoseini Soflaee, Andrei V. Karginov, Lawrence W. Miller
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09364-w

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