Double-edged sword of JAK/STAT signaling pathway in viral infections: novel insights into virotherapy

Double-edged sword of JAK/STAT signaling pathway in viral infections: novel insights into virotherapy

Abstract The Janus kinase/signal transducer and activator of transcription (JAK/STAT) is an intricate signaling cascade composed of various cytokines, interferons (IFN, growth factors, and other molecules. This pathway provides a delicate mechanism through which extracellular factors adjust gene exp...

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Bibliographic Details
Main Authors: Mohamad Mahjoor, Golnaz Mahmoudvand, Simin Farokhi, Alireza Shadab, Mojtaba Kashfi, Hamed Afkhami
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
JAK/STAT signaling pathway
Antiviral
Inflammation
Interferon
Cytokine
Online Access:https://doi.org/10.1186/s12964-023-01240-y

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