Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible Improvements
Antimicrobial resistance (AMR) is a public health problem worldwide. Bangladesh, like its neighboring countries, faces many public health challenges, including access to safe food, inadequate food surveillance, as well as increasing AMR. This study investigated bacterial contamination and the AMR pr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/12/3/555 |
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| author | Mohammed Abdus Samad Linnea Eberson Ruhena Begum Mohammad Gazi Shah Alam Faisol Talukdar Rahima Akter Sinh Dang-Xuan Garima Sharma Shariful Islam Nure Alam Siddiky ASM Ashab Uddin Mohammad Asheak Mahmud Md Samun Sarker Md. Siddiqur Rahman Delia Grace Johanna F. Lindahl |
| author_facet | Mohammed Abdus Samad Linnea Eberson Ruhena Begum Mohammad Gazi Shah Alam Faisol Talukdar Rahima Akter Sinh Dang-Xuan Garima Sharma Shariful Islam Nure Alam Siddiky ASM Ashab Uddin Mohammad Asheak Mahmud Md Samun Sarker Md. Siddiqur Rahman Delia Grace Johanna F. Lindahl |
| author_sort | Mohammed Abdus Samad |
| collection | DOAJ |
| description | Antimicrobial resistance (AMR) is a public health problem worldwide. Bangladesh, like its neighboring countries, faces many public health challenges, including access to safe food, inadequate food surveillance, as well as increasing AMR. This study investigated bacterial contamination and the AMR profile of pathogens in marketed food in Bangladesh and explored barriers to reducing AMR in the country. We collected 366 tomatoes, 359 chicken and 249 fish samples from 732 vendors in traditional markets in urban, peri-urban and rural areas in Bangladesh, as well as from 121 modern retails in Dhaka capital to analyse <i>Vibrio cholerae</i> and <i>Escherichia coli</i> in fish, <i>Salmonella</i> in chicken, and <i>Salmonella</i> and <i>E. coli</i> in tomatoes. Antibiotic susceptibility against 11 antibiotics was tested using a disc diffusion test and interpreted by an automated zone inhibition reader. In addition, a qualitative study using key informant interviews was conducted to explore antimicrobial use and AMR reduction potential in Bangladesh. We found <i>E. coli</i> in 14.21% of tomatoes and 26.91% of fish samples, while 7.38% of tomatoes and 17.27% of chicken were positive for <i>Salmonella</i>, and 44.98% of fish were positive for <i>Vibrio cholerae</i>. In total 231/319 (72.4%) of all pathogens isolated were multidrug-resistant (MDR) (resistant to three or more antibiotic groups). Qualitative interviews revealed an inadequate surveillance system for antibiotic use and AMR in Bangladesh, especially in the agriculture sector. To be able to fully understand the human health risks from bacterial hazards in the food and the AMR situation in Bangladesh, a nationwide study with a one health approach should be conducted, within all sectors, including AMR testing as well as assessment of the antimicrobial use and its drivers. |
| first_indexed | 2024-03-11T07:01:15Z |
| format | Article |
| id | doaj.art-2d844ec96415407b80cb7b2bda05ee73 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-11T07:01:15Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-2d844ec96415407b80cb7b2bda05ee732023-11-17T09:14:41ZengMDPI AGAntibiotics2079-63822023-03-0112355510.3390/antibiotics12030555Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible ImprovementsMohammed Abdus Samad0Linnea Eberson1Ruhena Begum2Mohammad Gazi Shah Alam3Faisol Talukdar4Rahima Akter5Sinh Dang-Xuan6Garima Sharma7Shariful Islam8Nure Alam Siddiky9ASM Ashab Uddin10Mohammad Asheak Mahmud11Md Samun Sarker12Md. Siddiqur Rahman13Delia Grace14Johanna F. Lindahl15Antimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, 75007 Uppsala, SwedenAntimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshDepartment of Livestock Services, Krishi Khamar Sarak, Dhaka 1215, BangladeshDepartment of Livestock Services, Krishi Khamar Sarak, Dhaka 1215, BangladeshAntimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshDepartment of Biosciences, International Livestock Research Institute, Hanoi 100000, VietnamDepartment of Biosciences, International Livestock Research Institute, Nairobi 00100, KenyaAntimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshAntimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshAntimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshAntimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshAntimicrobial Resistance Action Center, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, BangladeshDepartment of Medicine, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, BangladeshDepartment of Biosciences, International Livestock Research Institute, Nairobi 00100, KenyaDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, 75007 Uppsala, SwedenAntimicrobial resistance (AMR) is a public health problem worldwide. Bangladesh, like its neighboring countries, faces many public health challenges, including access to safe food, inadequate food surveillance, as well as increasing AMR. This study investigated bacterial contamination and the AMR profile of pathogens in marketed food in Bangladesh and explored barriers to reducing AMR in the country. We collected 366 tomatoes, 359 chicken and 249 fish samples from 732 vendors in traditional markets in urban, peri-urban and rural areas in Bangladesh, as well as from 121 modern retails in Dhaka capital to analyse <i>Vibrio cholerae</i> and <i>Escherichia coli</i> in fish, <i>Salmonella</i> in chicken, and <i>Salmonella</i> and <i>E. coli</i> in tomatoes. Antibiotic susceptibility against 11 antibiotics was tested using a disc diffusion test and interpreted by an automated zone inhibition reader. In addition, a qualitative study using key informant interviews was conducted to explore antimicrobial use and AMR reduction potential in Bangladesh. We found <i>E. coli</i> in 14.21% of tomatoes and 26.91% of fish samples, while 7.38% of tomatoes and 17.27% of chicken were positive for <i>Salmonella</i>, and 44.98% of fish were positive for <i>Vibrio cholerae</i>. In total 231/319 (72.4%) of all pathogens isolated were multidrug-resistant (MDR) (resistant to three or more antibiotic groups). Qualitative interviews revealed an inadequate surveillance system for antibiotic use and AMR in Bangladesh, especially in the agriculture sector. To be able to fully understand the human health risks from bacterial hazards in the food and the AMR situation in Bangladesh, a nationwide study with a one health approach should be conducted, within all sectors, including AMR testing as well as assessment of the antimicrobial use and its drivers.https://www.mdpi.com/2079-6382/12/3/555antimicrobial resistanceSouth Asiaantimicrobial usefood safetymultidrug-resistance (MDR)low-and middle-income countries |
| spellingShingle | Mohammed Abdus Samad Linnea Eberson Ruhena Begum Mohammad Gazi Shah Alam Faisol Talukdar Rahima Akter Sinh Dang-Xuan Garima Sharma Shariful Islam Nure Alam Siddiky ASM Ashab Uddin Mohammad Asheak Mahmud Md Samun Sarker Md. Siddiqur Rahman Delia Grace Johanna F. Lindahl Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible Improvements Antibiotics antimicrobial resistance South Asia antimicrobial use food safety multidrug-resistance (MDR) low-and middle-income countries |
| title | Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible Improvements |
| title_full | Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible Improvements |
| title_fullStr | Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible Improvements |
| title_full_unstemmed | Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible Improvements |
| title_short | Microbial Contamination and Antibiotic Resistance in Marketed Food in Bangladesh: Current Situation and Possible Improvements |
| title_sort | microbial contamination and antibiotic resistance in marketed food in bangladesh current situation and possible improvements |
| topic | antimicrobial resistance South Asia antimicrobial use food safety multidrug-resistance (MDR) low-and middle-income countries |
| url | https://www.mdpi.com/2079-6382/12/3/555 |
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