Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma

Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma

Many studies over the last 20 years have investigated the role of mitochondrial DNA (mtDNA) alterations in carcinogenesis. However, the status of the mtDNACN in MM and its implication in the pathogenesis of the disease remains unclear. We examined changes in plasma cell mtDNACN across different stag...

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Bibliographic Details
Main Authors: Yanira Ruiz-Heredia, Alejandra Ortiz-Ruiz, Mehmet K. Samur, Vanesa Garrido, Laura Rufian, Ricardo Sanchez, Pedro Aguilar-Garrido, Santiago Barrio, Miguel A. Martín, Niccolò Bolli, Yu-Tzu Tai, Raphaël Szalat, Mariateresa Fulciniti, Nikhil Munshi, Joaquín Martínez-López, María Linares, Miguel Gallardo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
multiple myeloma
smoldering MM
mitochondria DNA copy number
NGS
Online Access:https://www.mdpi.com/2072-6694/13/13/3189

Internet

https://www.mdpi.com/2072-6694/13/13/3189

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