Effect and potential mechanism of oncometabolite succinate promotes distant metastasis of colorectal cancer by activating STAT3

Effect and potential mechanism of oncometabolite succinate promotes distant metastasis of colorectal cancer by activating STAT3

Abstract To investigate the effect of Oncometabolite succinate on colorectal cancer migration and invasion and to initially explore the underlying mechanism.Succinate acid detection kit detected the succinate content in tissues. The growth of colorectal cancer cells was measured by cck-8 assay, woun...

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Bibliographic Details
Main Authors: Jiangnan Yu, Hong Yang, Lin Zhang, Suye Ran, Qing Shi, Pailan Peng, Qi Liu, Lingyu Song
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Gastroenterology
Subjects:
Colorectal cancer
Succinate
STAT3
Migration and invasion
Epithelial-stromal transition
Online Access:https://doi.org/10.1186/s12876-024-03195-x

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