Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis

Hang Cheng,1 Jeffrey W Clymer,1 Rana A Qadeer,2 Nicole Ferko,2 Behnam Sadeghirad,2 Chris G Cameron,2 Joseph F Amaral1 1Ethicon Inc, Cincinnati, OH, USA; 2Cornerstone Research Group, Burlington, ON, Canada Background: As compared to conventional techniques, recent meta-analyses have reported cost sav...

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Main Authors: Cheng H, Clymer JW, Qadeer RA, Ferko N, Sadeghirad B, Cameron CG, Amaral JF
Format: Article
Language:English
Published: Dove Medical Press 2018-07-01
Series:ClinicoEconomics and Outcomes Research
Subjects:
Online Access:https://www.dovepress.com/procedure-costs-associated-with-the-use-of-harmonic-devices-compared-t-peer-reviewed-article-CEOR
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author Cheng H
Clymer JW
Qadeer RA
Ferko N
Sadeghirad B
Cameron CG
Amaral JF
author_facet Cheng H
Clymer JW
Qadeer RA
Ferko N
Sadeghirad B
Cameron CG
Amaral JF
author_sort Cheng H
collection DOAJ
description Hang Cheng,1 Jeffrey W Clymer,1 Rana A Qadeer,2 Nicole Ferko,2 Behnam Sadeghirad,2 Chris G Cameron,2 Joseph F Amaral1 1Ethicon Inc, Cincinnati, OH, USA; 2Cornerstone Research Group, Burlington, ON, Canada Background: As compared to conventional techniques, recent meta-analyses have reported cost savings with Harmonic devices; however, only in thyroidectomy. Thus, the aim of this study was to evaluate the costs associated with Harmonic devices versus conventional techniques across a range of surgical procedures. Methods: A systematic search of MEDLINE, EMBASE, and Cochrane Library was conducted from inception to October 01, 2016 without language restrictions to identify randomized controlled trials comparing Harmonic devices to conventional techniques and reporting procedure costs (operating time plus operating equipment/consumables/device costs). Costs were pooled using the ratio of geometric means, and a random effects model was applied. Sensitivity analyses varying statistical methods, number of included studies, and cost outcomes were completed to test the robustness of the results. Results: Thirteen studies met the inclusion criteria. A total of 561 and 540 participants had procedures performed with Harmonic devices and conventional methods, respectively, with procedures including gastrectomy, thyroidectomy, colectomy, cholecystectomy, Nissen fundoplication, and pancreaticoduodenectomy. As compared to conventional methods, Harmonic devices reduced total procedure costs by 8.7% (p=0.029), resulting in an absolute reduction of US$227.77 from mean conventional technique costs, derived primarily from a reduction in operating time costs. When operating time costs, excluding operating equipment/consumables/device costs, were analyzed, costs were reduced by $544 per procedure with the use of Harmonic devices. The results from all sensitivity analyses demonstrated cost reductions with Harmonic devices. Conclusion: This systematic review and meta-analysis showed that despite a higher device cost, Harmonic devices provide a statistically significant reduction in procedure costs, derived primarily from a reduction in operating time costs, across surgical procedures. In addition to functionality benefits, Harmonic devices may represent a potentially cost saving method to reduce overall hospital resource use. Future research should focus on potential costs and benefits from use of Harmonic devices in procedures not covered here. Keywords: Harmonic, ultrasonic, meta-analysis, costs, surgery, efficiency, operating time
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spelling doaj.art-2d8c1952e07344ff9558ac36127c56ba2022-12-21T19:03:43ZengDove Medical PressClinicoEconomics and Outcomes Research1178-69812018-07-01Volume 1039941239489Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysisCheng HClymer JWQadeer RAFerko NSadeghirad BCameron CGAmaral JFHang Cheng,1 Jeffrey W Clymer,1 Rana A Qadeer,2 Nicole Ferko,2 Behnam Sadeghirad,2 Chris G Cameron,2 Joseph F Amaral1 1Ethicon Inc, Cincinnati, OH, USA; 2Cornerstone Research Group, Burlington, ON, Canada Background: As compared to conventional techniques, recent meta-analyses have reported cost savings with Harmonic devices; however, only in thyroidectomy. Thus, the aim of this study was to evaluate the costs associated with Harmonic devices versus conventional techniques across a range of surgical procedures. Methods: A systematic search of MEDLINE, EMBASE, and Cochrane Library was conducted from inception to October 01, 2016 without language restrictions to identify randomized controlled trials comparing Harmonic devices to conventional techniques and reporting procedure costs (operating time plus operating equipment/consumables/device costs). Costs were pooled using the ratio of geometric means, and a random effects model was applied. Sensitivity analyses varying statistical methods, number of included studies, and cost outcomes were completed to test the robustness of the results. Results: Thirteen studies met the inclusion criteria. A total of 561 and 540 participants had procedures performed with Harmonic devices and conventional methods, respectively, with procedures including gastrectomy, thyroidectomy, colectomy, cholecystectomy, Nissen fundoplication, and pancreaticoduodenectomy. As compared to conventional methods, Harmonic devices reduced total procedure costs by 8.7% (p=0.029), resulting in an absolute reduction of US$227.77 from mean conventional technique costs, derived primarily from a reduction in operating time costs. When operating time costs, excluding operating equipment/consumables/device costs, were analyzed, costs were reduced by $544 per procedure with the use of Harmonic devices. The results from all sensitivity analyses demonstrated cost reductions with Harmonic devices. Conclusion: This systematic review and meta-analysis showed that despite a higher device cost, Harmonic devices provide a statistically significant reduction in procedure costs, derived primarily from a reduction in operating time costs, across surgical procedures. In addition to functionality benefits, Harmonic devices may represent a potentially cost saving method to reduce overall hospital resource use. Future research should focus on potential costs and benefits from use of Harmonic devices in procedures not covered here. Keywords: Harmonic, ultrasonic, meta-analysis, costs, surgery, efficiency, operating timehttps://www.dovepress.com/procedure-costs-associated-with-the-use-of-harmonic-devices-compared-t-peer-reviewed-article-CEORHarmonicUltrasonicMeta-analysisCosts
spellingShingle Cheng H
Clymer JW
Qadeer RA
Ferko N
Sadeghirad B
Cameron CG
Amaral JF
Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis
ClinicoEconomics and Outcomes Research
Harmonic
Ultrasonic
Meta-analysis
Costs
title Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis
title_full Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis
title_fullStr Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis
title_full_unstemmed Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis
title_short Procedure costs associated with the use of Harmonic devices compared to conventional techniques in various surgeries: a systematic review and meta-analysis
title_sort procedure costs associated with the use of harmonic devices compared to conventional techniques in various surgeries a systematic review and meta analysis
topic Harmonic
Ultrasonic
Meta-analysis
Costs
url https://www.dovepress.com/procedure-costs-associated-with-the-use-of-harmonic-devices-compared-t-peer-reviewed-article-CEOR
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