Autoantibodies and SARS-CoV-2 infection: A case report

The article describes a COVID-19 patient with several biomarkers of systemic cytokine storm (including multiple excess over the reference values of C-reactive protein, ferritin and D-dimer) and increased level of autoantibodies (aPL and anti-CCP). At the same time contrast-enhanced CT and US failed...

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Main Authors: T. I. Kalenchic, S. L. Kabak, I. V. Korenevskaya
Format: Article
Language:Russian
Published: IMA PRESS LLC 2022-07-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/3175
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author T. I. Kalenchic
S. L. Kabak
I. V. Korenevskaya
author_facet T. I. Kalenchic
S. L. Kabak
I. V. Korenevskaya
author_sort T. I. Kalenchic
collection DOAJ
description The article describes a COVID-19 patient with several biomarkers of systemic cytokine storm (including multiple excess over the reference values of C-reactive protein, ferritin and D-dimer) and increased level of autoantibodies (aPL and anti-CCP). At the same time contrast-enhanced CT and US failed to detect pulmonary embolism or lower limb deep vein thrombosis. Three months after discharge from the hospital, a high level of antiphospholipid antibodies and D-dimer remained. The relationship between infection with SARS-CoV-2 and autoimmunity has been discussed.
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spelling doaj.art-2d8ee39b3c264d25bf93b9eb6515dd902023-03-22T13:45:57ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922022-07-0160327127510.47360/1995-4484-2022-271-2752807Autoantibodies and SARS-CoV-2 infection: A case reportT. I. Kalenchic0S. L. Kabak1I. V. Korenevskaya2Belarussian State Medical UniversityBelarussian State Medical University6th City Clinical HospitalThe article describes a COVID-19 patient with several biomarkers of systemic cytokine storm (including multiple excess over the reference values of C-reactive protein, ferritin and D-dimer) and increased level of autoantibodies (aPL and anti-CCP). At the same time contrast-enhanced CT and US failed to detect pulmonary embolism or lower limb deep vein thrombosis. Three months after discharge from the hospital, a high level of antiphospholipid antibodies and D-dimer remained. The relationship between infection with SARS-CoV-2 and autoimmunity has been discussed.https://rsp.mediar-press.net/rsp/article/view/3175covid-19autoimmune diseasesanti-cyclic citrullinated peptide antibodiesanti-cardiolipin antibodiesanti-β(2)-glycoprotein antibodies
spellingShingle T. I. Kalenchic
S. L. Kabak
I. V. Korenevskaya
Autoantibodies and SARS-CoV-2 infection: A case report
Научно-практическая ревматология
covid-19
autoimmune diseases
anti-cyclic citrullinated peptide antibodies
anti-cardiolipin antibodies
anti-β(2)-glycoprotein antibodies
title Autoantibodies and SARS-CoV-2 infection: A case report
title_full Autoantibodies and SARS-CoV-2 infection: A case report
title_fullStr Autoantibodies and SARS-CoV-2 infection: A case report
title_full_unstemmed Autoantibodies and SARS-CoV-2 infection: A case report
title_short Autoantibodies and SARS-CoV-2 infection: A case report
title_sort autoantibodies and sars cov 2 infection a case report
topic covid-19
autoimmune diseases
anti-cyclic citrullinated peptide antibodies
anti-cardiolipin antibodies
anti-β(2)-glycoprotein antibodies
url https://rsp.mediar-press.net/rsp/article/view/3175
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AT slkabak autoantibodiesandsarscov2infectionacasereport
AT ivkorenevskaya autoantibodiesandsarscov2infectionacasereport