UCHL5 Promotes Proliferation and Migration of Bladder Cancer Cells by Activating c-Myc via AKT/mTOR Signaling

UCHL5 Promotes Proliferation and Migration of Bladder Cancer Cells by Activating c-Myc via AKT/mTOR Signaling

Ubiquitin C-terminal hydrolase L5 (UCHL5) is a deubiquitinating enzyme (DUB) that removes ubiquitin from its substrates. Associations between UCHL5 and cancer have been reported in various tissues, but the effect of UCHL5 on bladder cancer has not been thoroughly investigated. This study investigate...

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Bibliographic Details
Main Authors: Yuanfei Cao, Xin Yan, Xiaojie Bai, Feng Tang, Penghui Si, Can Bai, Kuerban Tuoheti, Linfa Guo, Zuhaer Yisha, Tao Liu, Tongzu Liu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
UCHL5
bladder cancer
proliferation
migration
AKT
c-Myc
Online Access:https://www.mdpi.com/2072-6694/14/22/5538

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