Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection
Abstract Point‐of‐care devices that are inexpensive, disposable, and environmentally friendly are becoming increasingly predominant in the field of biosensing and biodiagnostics. Here, microfluidics is a suitable option to endow portability and minimal reagent and material consumption. Nanocellulose...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-02-01
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| Series: | Global Challenges |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/gch2.201800079 |
| _version_ | 1797743705343393792 |
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| author | Khan Mohammad Ahsan Uddin Ville Jokinen Farzin Jahangiri Sami Franssila Orlando J. Rojas Sampo Tuukkanen |
| author_facet | Khan Mohammad Ahsan Uddin Ville Jokinen Farzin Jahangiri Sami Franssila Orlando J. Rojas Sampo Tuukkanen |
| author_sort | Khan Mohammad Ahsan Uddin |
| collection | DOAJ |
| description | Abstract Point‐of‐care devices that are inexpensive, disposable, and environmentally friendly are becoming increasingly predominant in the field of biosensing and biodiagnostics. Here, microfluidics is a suitable option to endow portability and minimal reagent and material consumption. Nanocellulose is introduced to manufacture microfluidic channels and as a storage and immobilization compartment of glucose oxidase. Improved enzymatic activity retention is demonstrated in a simple and disposable point‐of‐care diagnostic unit that is able to detect glucose from fluid matrices at 0.1 × 10−3m concentration and in less than 10 min. It is concluded that the patterning and fluidic technologies that are possible with nanocellulose enable easily scalable multianalyte designs. |
| first_indexed | 2024-03-12T14:59:16Z |
| format | Article |
| id | doaj.art-2d9f20bd7deb429591a5b5d368b5f44b |
| institution | Directory Open Access Journal |
| issn | 2056-6646 |
| language | English |
| last_indexed | 2024-03-12T14:59:16Z |
| publishDate | 2019-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Global Challenges |
| spelling | doaj.art-2d9f20bd7deb429591a5b5d368b5f44b2023-08-14T09:40:30ZengWileyGlobal Challenges2056-66462019-02-0132n/an/a10.1002/gch2.201800079Disposable Microfluidic Sensor Based on Nanocellulose for Glucose DetectionKhan Mohammad Ahsan Uddin0Ville Jokinen1Farzin Jahangiri2Sami Franssila3Orlando J. Rojas4Sampo Tuukkanen5BioMediTech Institute and Faculty of Biomedical Sciences and Engineering Tampere University of Technology (TUT) Post address: P.O. Box 692 FI‐33101 Tampere FinlandDepartment of Chemistry and Materials Science School of Chemical Engineering and Micronova Nanofabrication Centre Aalto University Espoo P.O. Box 13500 FI‐00076 Aalto FinlandDepartment of Chemistry and Materials Science School of Chemical Engineering and Micronova Nanofabrication Centre Aalto University Espoo P.O. Box 13500 FI‐00076 Aalto FinlandDepartment of Chemistry and Materials Science School of Chemical Engineering and Micronova Nanofabrication Centre Aalto University Espoo P.O. Box 13500 FI‐00076 Aalto FinlandDepartment of Bioproducts and Biosystems School of Chemical Engineering Aalto University Espoo P.O. Box 16300 FI‐00076 Aalto FinlandBioMediTech Institute and Faculty of Biomedical Sciences and Engineering Tampere University of Technology (TUT) Post address: P.O. Box 692 FI‐33101 Tampere FinlandAbstract Point‐of‐care devices that are inexpensive, disposable, and environmentally friendly are becoming increasingly predominant in the field of biosensing and biodiagnostics. Here, microfluidics is a suitable option to endow portability and minimal reagent and material consumption. Nanocellulose is introduced to manufacture microfluidic channels and as a storage and immobilization compartment of glucose oxidase. Improved enzymatic activity retention is demonstrated in a simple and disposable point‐of‐care diagnostic unit that is able to detect glucose from fluid matrices at 0.1 × 10−3m concentration and in less than 10 min. It is concluded that the patterning and fluidic technologies that are possible with nanocellulose enable easily scalable multianalyte designs.https://doi.org/10.1002/gch2.201800079biosensorscolorimetrydiagnosticsglucose oxidasenanofibrils |
| spellingShingle | Khan Mohammad Ahsan Uddin Ville Jokinen Farzin Jahangiri Sami Franssila Orlando J. Rojas Sampo Tuukkanen Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection Global Challenges biosensors colorimetry diagnostics glucose oxidase nanofibrils |
| title | Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection |
| title_full | Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection |
| title_fullStr | Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection |
| title_full_unstemmed | Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection |
| title_short | Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection |
| title_sort | disposable microfluidic sensor based on nanocellulose for glucose detection |
| topic | biosensors colorimetry diagnostics glucose oxidase nanofibrils |
| url | https://doi.org/10.1002/gch2.201800079 |
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