Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers
INTRODUCTION[|]Vitamin D deficiency may play a role in the pathogenesis of preeclampsia by causing abnormal placental implantation and by affecting the inflammatory response. The aim of this study was to compare the cord blood vitamin D level in neonates born to preeclamptic mothers with that of a c...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KARE Publishing
2019-07-01
|
| Series: | Southern Clinics of Istanbul Eurasia |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-72692 |
| _version_ | 1797907208878424064 |
|---|---|
| author | Didem Arman Secil Ercin Sevilay Topcuoğlu Ayşem Kaya Fahri Ovalı Guner Karatekin |
| author_facet | Didem Arman Secil Ercin Sevilay Topcuoğlu Ayşem Kaya Fahri Ovalı Guner Karatekin |
| author_sort | Didem Arman |
| collection | DOAJ |
| description | INTRODUCTION[|]Vitamin D deficiency may play a role in the pathogenesis of preeclampsia by causing abnormal placental implantation and by affecting the inflammatory response. The aim of this study was to compare the cord blood vitamin D level in neonates born to preeclamptic mothers with that of a control group of newborns whose mothers were not preeclamptic.[¤]METHODS[|]The preeclamptic group was made up of newborns of mothers classified as having moderate to severe preeclampsia. Neonates of a similar gestational age and birth weight born to normotensive mothers comprised the control group. The cord blood vitamin D level of both groups of newborns was measured and the results were statistically compared. [¤]RESULTS[|]Sixty neonates born to preeclamptic mothers and 47 born to normotensive mothers were included in the study. The mean serum vitamin D level of the study group was 12.62+-5.43 ng/mL and 12.85+-5.56 ng/mL in the control group. The percentage of those determined to have a serum vitamin D level <20 ng/mL in the study and the control groups was 89.5% and 88.9%, respectively. The serum magnesium level in the study group was statistically greater than that observed in the control group (p<0.001).[¤]DISCUSSION AND CONCLUSION[|]The cord blood vitamin D level of those born to preeclamptic mothers was not found to be statistically different when compared with the vitamin D level of neonates of normotensive mothers.[¤] |
| first_indexed | 2024-04-10T10:32:57Z |
| format | Article |
| id | doaj.art-2da134595741468284430a233e601a4e |
| institution | Directory Open Access Journal |
| issn | 2587-0998 |
| language | English |
| last_indexed | 2024-04-10T10:32:57Z |
| publishDate | 2019-07-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Southern Clinics of Istanbul Eurasia |
| spelling | doaj.art-2da134595741468284430a233e601a4e2023-02-15T16:21:02ZengKARE PublishingSouthern Clinics of Istanbul Eurasia2587-09982019-07-0130210711110.14744/scie.2019.72692SCIE-72692Cord Blood Vitamin D Level in Neonates of Preeclamptic MothersDidem Arman0Secil Ercin1Sevilay Topcuoğlu2Ayşem Kaya3Fahri Ovalı4Guner Karatekin5Department of Pediatrics, Division of Neonatology, University of Health Sciences Zeynep Kamil Maternity and Children's Training and Research Hospital, İstanbul, TurkeyDepartment of Pediatrics, Division of Neonatology, American Hospital, İstanbul, TurkeyDepartment of Pediatrics, Division of Neonatology, University of Health Sciences Zeynep Kamil Maternity and Children's Training and Research Hospital, İstanbul, TurkeyDepartment of Biochemistry, Institute of Cardiology, İstanbul University, İstanbul, TurkeyDepartment of Pediatrics, Neonatal Intensive Care Unit, İstanbul Medeniyet University Göztepe Training and Research Hospital İstanbul, TurkeyDepartment of Pediatrics, Division of Neonatology, University of Health Sciences Zeynep Kamil Maternity and Children's Training and Research Hospital, İstanbul, TurkeyINTRODUCTION[|]Vitamin D deficiency may play a role in the pathogenesis of preeclampsia by causing abnormal placental implantation and by affecting the inflammatory response. The aim of this study was to compare the cord blood vitamin D level in neonates born to preeclamptic mothers with that of a control group of newborns whose mothers were not preeclamptic.[¤]METHODS[|]The preeclamptic group was made up of newborns of mothers classified as having moderate to severe preeclampsia. Neonates of a similar gestational age and birth weight born to normotensive mothers comprised the control group. The cord blood vitamin D level of both groups of newborns was measured and the results were statistically compared. [¤]RESULTS[|]Sixty neonates born to preeclamptic mothers and 47 born to normotensive mothers were included in the study. The mean serum vitamin D level of the study group was 12.62+-5.43 ng/mL and 12.85+-5.56 ng/mL in the control group. The percentage of those determined to have a serum vitamin D level <20 ng/mL in the study and the control groups was 89.5% and 88.9%, respectively. The serum magnesium level in the study group was statistically greater than that observed in the control group (p<0.001).[¤]DISCUSSION AND CONCLUSION[|]The cord blood vitamin D level of those born to preeclamptic mothers was not found to be statistically different when compared with the vitamin D level of neonates of normotensive mothers.[¤]https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-72692cord bloodpreeclampsia; vitamin d. |
| spellingShingle | Didem Arman Secil Ercin Sevilay Topcuoğlu Ayşem Kaya Fahri Ovalı Guner Karatekin Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers Southern Clinics of Istanbul Eurasia cord blood preeclampsia; vitamin d. |
| title | Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers |
| title_full | Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers |
| title_fullStr | Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers |
| title_full_unstemmed | Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers |
| title_short | Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers |
| title_sort | cord blood vitamin d level in neonates of preeclamptic mothers |
| topic | cord blood preeclampsia; vitamin d. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-72692 |
| work_keys_str_mv | AT didemarman cordbloodvitamindlevelinneonatesofpreeclampticmothers AT secilercin cordbloodvitamindlevelinneonatesofpreeclampticmothers AT sevilaytopcuoglu cordbloodvitamindlevelinneonatesofpreeclampticmothers AT aysemkaya cordbloodvitamindlevelinneonatesofpreeclampticmothers AT fahriovalı cordbloodvitamindlevelinneonatesofpreeclampticmothers AT gunerkaratekin cordbloodvitamindlevelinneonatesofpreeclampticmothers |