Prevalence of Haemoglobine s in Araraquara-SP Population.
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle shape (sickle-cell), a sickling phenomenon, whi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Portuguese |
| Published: |
Maria Lúcia Ribeiro,
2015-01-01
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| Series: | Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal |
| Subjects: | |
| Online Access: | http://www.revistarebram.com/index.php/revistauniara/article/view/194 |
| _version_ | 1797721114857701376 |
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| author | Bruno Rocha de Jesus Heloise Brait Rin Elza Regina Manzolli Leite Amauri Antiquera Leite Miriane da Costa Gileno |
| author_facet | Bruno Rocha de Jesus Heloise Brait Rin Elza Regina Manzolli Leite Amauri Antiquera Leite Miriane da Costa Gileno |
| author_sort | Bruno Rocha de Jesus |
| collection | DOAJ |
| description | The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle shape (sickle-cell), a sickling phenomenon, which leads to severe anemia in homozygous, while sickle cell trait (heterozygote) leads to pain crisis, according to pathophysiology, in low O2 blood pressure situations. The most specific and sensitive test used to diagnose this anemia is the hemoglobin eletrophoresis test, which is, however, hard to be incorporated in routine laboratories, due to its high cost. The objective of this work was to estimate the sickle cell trait prevalence in Araraquara - SP population. The prevalence of asymptomatic individuals with the sickle cell trait was 1.5%. Considering the study of race prevalence, 0,6% of sickle cell trait in white individuals and 15,4% in black ones were found. |
| first_indexed | 2024-03-12T09:29:00Z |
| format | Article |
| id | doaj.art-2da36496e8184d309662ed4acec76b22 |
| institution | Directory Open Access Journal |
| issn | 1415-3580 2527-2675 |
| language | Portuguese |
| last_indexed | 2024-03-12T09:29:00Z |
| publishDate | 2015-01-01 |
| publisher | Maria Lúcia Ribeiro, |
| record_format | Article |
| series | Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal |
| spelling | doaj.art-2da36496e8184d309662ed4acec76b222023-09-02T13:58:07ZporMaria Lúcia Ribeiro,Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal1415-35802527-26752015-01-0111223023710.25061/2527-2675/ReBraM/2007.v11i2.194162Prevalence of Haemoglobine s in Araraquara-SP Population.Bruno Rocha de Jesus0Heloise Brait Rin1Elza Regina Manzolli Leite2Amauri Antiquera Leite3Miriane da Costa Gileno4Centro Universitário de Araraquara – Uniara.Centro Universitário de Araraquara – Uniara.(FCF UNESP) AraraquaraUNESP(FCF UNESP) / Uniara.The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle shape (sickle-cell), a sickling phenomenon, which leads to severe anemia in homozygous, while sickle cell trait (heterozygote) leads to pain crisis, according to pathophysiology, in low O2 blood pressure situations. The most specific and sensitive test used to diagnose this anemia is the hemoglobin eletrophoresis test, which is, however, hard to be incorporated in routine laboratories, due to its high cost. The objective of this work was to estimate the sickle cell trait prevalence in Araraquara - SP population. The prevalence of asymptomatic individuals with the sickle cell trait was 1.5%. Considering the study of race prevalence, 0,6% of sickle cell trait in white individuals and 15,4% in black ones were found.http://www.revistarebram.com/index.php/revistauniara/article/view/194Anemia, Hemoglobinas, Falciforme, Falcização, Solubilidade |
| spellingShingle | Bruno Rocha de Jesus Heloise Brait Rin Elza Regina Manzolli Leite Amauri Antiquera Leite Miriane da Costa Gileno Prevalence of Haemoglobine s in Araraquara-SP Population. Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal Anemia, Hemoglobinas, Falciforme, Falcização, Solubilidade |
| title | Prevalence of Haemoglobine s in Araraquara-SP Population. |
| title_full | Prevalence of Haemoglobine s in Araraquara-SP Population. |
| title_fullStr | Prevalence of Haemoglobine s in Araraquara-SP Population. |
| title_full_unstemmed | Prevalence of Haemoglobine s in Araraquara-SP Population. |
| title_short | Prevalence of Haemoglobine s in Araraquara-SP Population. |
| title_sort | prevalence of haemoglobine s in araraquara sp population |
| topic | Anemia, Hemoglobinas, Falciforme, Falcização, Solubilidade |
| url | http://www.revistarebram.com/index.php/revistauniara/article/view/194 |
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