Colon cancer and their targeting approaches through nanocarriers: A review

Colon cancer is the fifth most common type of cancer in the world. Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor. Despite major medical improvements, colon cancer is still one of the leading causes of cance...

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Main Authors: Richa Kumari, Nitin Sharma, Ritu Karwasra, Kushagra Khanna
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=3;spage=104;epage=111;aulast=Kumari
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author Richa Kumari
Nitin Sharma
Ritu Karwasra
Kushagra Khanna
author_facet Richa Kumari
Nitin Sharma
Ritu Karwasra
Kushagra Khanna
author_sort Richa Kumari
collection DOAJ
description Colon cancer is the fifth most common type of cancer in the world. Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor. Despite major medical improvements, colon cancer is still one of the leading causes of cancer-related mortality globally. One of the main issues of chemotherapy is toxicity related to conventional medicines. The targeted delivery systems are considered the safest and most effective by increasing the concentration of a therapeutic substance at the tumor site while decreasing it at other organs. Therefore, these delivery systems required lower doses for high therapeutic value with minimum side effects. The current review focuses on targeting therapeutic substances at the desired site using nanocarriers. Additionally, the diagnostic applications of nanocarriers in colorectal cancer are also discussed.
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spelling doaj.art-2da665a31c794c599c29ae240d5089a12024-05-25T11:45:34ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Biomedicine2221-16912588-92222023-01-0113310411110.4103/2221-1691.372283Colon cancer and their targeting approaches through nanocarriers: A reviewRicha KumariNitin SharmaRitu KarwasraKushagra KhannaColon cancer is the fifth most common type of cancer in the world. Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor. Despite major medical improvements, colon cancer is still one of the leading causes of cancer-related mortality globally. One of the main issues of chemotherapy is toxicity related to conventional medicines. The targeted delivery systems are considered the safest and most effective by increasing the concentration of a therapeutic substance at the tumor site while decreasing it at other organs. Therefore, these delivery systems required lower doses for high therapeutic value with minimum side effects. The current review focuses on targeting therapeutic substances at the desired site using nanocarriers. Additionally, the diagnostic applications of nanocarriers in colorectal cancer are also discussed.http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=3;spage=104;epage=111;aulast=Kumaricolon cancer; targeting approaches; chemotherapies; nanocarriers; gold nanoparticles; liposomes
spellingShingle Richa Kumari
Nitin Sharma
Ritu Karwasra
Kushagra Khanna
Colon cancer and their targeting approaches through nanocarriers: A review
Asian Pacific Journal of Tropical Biomedicine
colon cancer; targeting approaches; chemotherapies; nanocarriers; gold nanoparticles; liposomes
title Colon cancer and their targeting approaches through nanocarriers: A review
title_full Colon cancer and their targeting approaches through nanocarriers: A review
title_fullStr Colon cancer and their targeting approaches through nanocarriers: A review
title_full_unstemmed Colon cancer and their targeting approaches through nanocarriers: A review
title_short Colon cancer and their targeting approaches through nanocarriers: A review
title_sort colon cancer and their targeting approaches through nanocarriers a review
topic colon cancer; targeting approaches; chemotherapies; nanocarriers; gold nanoparticles; liposomes
url http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=3;spage=104;epage=111;aulast=Kumari
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AT nitinsharma coloncancerandtheirtargetingapproachesthroughnanocarriersareview
AT ritukarwasra coloncancerandtheirtargetingapproachesthroughnanocarriersareview
AT kushagrakhanna coloncancerandtheirtargetingapproachesthroughnanocarriersareview