Colon cancer and their targeting approaches through nanocarriers: A review
Colon cancer is the fifth most common type of cancer in the world. Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor. Despite major medical improvements, colon cancer is still one of the leading causes of cance...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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Series: | Asian Pacific Journal of Tropical Biomedicine |
Subjects: | |
Online Access: | http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=3;spage=104;epage=111;aulast=Kumari |
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author | Richa Kumari Nitin Sharma Ritu Karwasra Kushagra Khanna |
author_facet | Richa Kumari Nitin Sharma Ritu Karwasra Kushagra Khanna |
author_sort | Richa Kumari |
collection | DOAJ |
description | Colon cancer is the fifth most common type of cancer in the world. Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor. Despite major medical improvements, colon cancer is still one of the leading causes of cancer-related mortality globally. One of the main issues of chemotherapy is toxicity related to conventional medicines. The targeted delivery systems are considered the safest and most effective by increasing the concentration of a therapeutic substance at the tumor site while decreasing it at other organs. Therefore, these delivery systems required lower doses for high therapeutic value with minimum side effects. The current review focuses on targeting therapeutic substances at the desired site using nanocarriers. Additionally, the diagnostic applications of nanocarriers in colorectal cancer are also discussed. |
first_indexed | 2024-03-13T10:38:48Z |
format | Article |
id | doaj.art-2da665a31c794c599c29ae240d5089a1 |
institution | Directory Open Access Journal |
issn | 2221-1691 2588-9222 |
language | English |
last_indexed | 2025-03-21T22:02:20Z |
publishDate | 2023-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Asian Pacific Journal of Tropical Biomedicine |
spelling | doaj.art-2da665a31c794c599c29ae240d5089a12024-05-25T11:45:34ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Biomedicine2221-16912588-92222023-01-0113310411110.4103/2221-1691.372283Colon cancer and their targeting approaches through nanocarriers: A reviewRicha KumariNitin SharmaRitu KarwasraKushagra KhannaColon cancer is the fifth most common type of cancer in the world. Colon cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a tumor. Despite major medical improvements, colon cancer is still one of the leading causes of cancer-related mortality globally. One of the main issues of chemotherapy is toxicity related to conventional medicines. The targeted delivery systems are considered the safest and most effective by increasing the concentration of a therapeutic substance at the tumor site while decreasing it at other organs. Therefore, these delivery systems required lower doses for high therapeutic value with minimum side effects. The current review focuses on targeting therapeutic substances at the desired site using nanocarriers. Additionally, the diagnostic applications of nanocarriers in colorectal cancer are also discussed.http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=3;spage=104;epage=111;aulast=Kumaricolon cancer; targeting approaches; chemotherapies; nanocarriers; gold nanoparticles; liposomes |
spellingShingle | Richa Kumari Nitin Sharma Ritu Karwasra Kushagra Khanna Colon cancer and their targeting approaches through nanocarriers: A review Asian Pacific Journal of Tropical Biomedicine colon cancer; targeting approaches; chemotherapies; nanocarriers; gold nanoparticles; liposomes |
title | Colon cancer and their targeting approaches through nanocarriers: A review |
title_full | Colon cancer and their targeting approaches through nanocarriers: A review |
title_fullStr | Colon cancer and their targeting approaches through nanocarriers: A review |
title_full_unstemmed | Colon cancer and their targeting approaches through nanocarriers: A review |
title_short | Colon cancer and their targeting approaches through nanocarriers: A review |
title_sort | colon cancer and their targeting approaches through nanocarriers a review |
topic | colon cancer; targeting approaches; chemotherapies; nanocarriers; gold nanoparticles; liposomes |
url | http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=3;spage=104;epage=111;aulast=Kumari |
work_keys_str_mv | AT richakumari coloncancerandtheirtargetingapproachesthroughnanocarriersareview AT nitinsharma coloncancerandtheirtargetingapproachesthroughnanocarriersareview AT ritukarwasra coloncancerandtheirtargetingapproachesthroughnanocarriersareview AT kushagrakhanna coloncancerandtheirtargetingapproachesthroughnanocarriersareview |