Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations

Abstract The precise temporal coordination of neural activity is crucial for brain function. In the hippocampus, this precision is reflected in the oscillatory rhythms observed in CA1. While it is known that a balance between excitatory and inhibitory activity is necessary to generate and maintain t...

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Bibliographic Details
Main Authors: Chinnakkaruppan Adaikkan, Justin Joseph, Georgios Foustoukos, Jun Wang, Denis Polygalov, Roman Boehringer, Steven J. Middleton, Arthur J. Y. Huang, Li-Huei Tsai, Thomas J. McHugh
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46478-3