The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva
Objective To investigate the efficacy, safety, and influencing factors of secondary focused ultrasound (FU) therapy for recurrence of non-neoplastic epithelial disorders of the vulva (NNEDV).Methods Patients with NNEDV who have relapsed after initial FU treatment were included in this study. They we...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-12-01
|
| Series: | International Journal of Hyperthermia |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2022.2131000 |
| _version_ | 1817980943748562944 |
|---|---|
| author | Ruizhen Li Jianfa Jiang |
| author_facet | Ruizhen Li Jianfa Jiang |
| author_sort | Ruizhen Li |
| collection | DOAJ |
| description | Objective To investigate the efficacy, safety, and influencing factors of secondary focused ultrasound (FU) therapy for recurrence of non-neoplastic epithelial disorders of the vulva (NNEDV).Methods Patients with NNEDV who have relapsed after initial FU treatment were included in this study. They were treated with secondary FU therapy between July 2015 and July 2021. Outcome measures included the degree of symptom severity and operative complications. We further analyzed the relationships between age, course, time between relapse and initial treatment, menopause status, lesion size, pathological types, severity of symptoms, and curative rate.Results There were 98 patients enrolled in this study, with a mean age of 47.4 ± 11.4 years. All patients successfully underwent secondary FU therapy. Blisters developed among 16 (16.3%) patients, of whom 6 (6.1%) developed superficial skin ulcers. A curative response was observed among 46 (46.9%) patients, while an effective response was observed among 44 (44.9%) patients. Only 8 (8.2%) patients showed no improvement. The total response rate was 91.8%. A total of 12 (12.2%) cases recurred among all effective cases. Patients with a recurrence of NNEDV after more than 1.5 years following their first FU therapy demonstrated a higher response rate than those with a recurrence after less than 1.5 years.Conclusions A second FU therapy remains effective for patients with recurrent NNEDV with no obvious side effects. The response rate, however, is higher for patients who experience recurrence of NNDEDV after more than 1.5 years. |
| first_indexed | 2024-04-13T22:59:19Z |
| format | Article |
| id | doaj.art-2da9d2c17a204dadaa5d5bfde8fbdf42 |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-04-13T22:59:19Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-2da9d2c17a204dadaa5d5bfde8fbdf422022-12-22T02:25:53ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572022-12-013911310131410.1080/02656736.2022.2131000The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulvaRuizhen Li0Jianfa Jiang1Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, ChinaDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, Changsha, ChinaObjective To investigate the efficacy, safety, and influencing factors of secondary focused ultrasound (FU) therapy for recurrence of non-neoplastic epithelial disorders of the vulva (NNEDV).Methods Patients with NNEDV who have relapsed after initial FU treatment were included in this study. They were treated with secondary FU therapy between July 2015 and July 2021. Outcome measures included the degree of symptom severity and operative complications. We further analyzed the relationships between age, course, time between relapse and initial treatment, menopause status, lesion size, pathological types, severity of symptoms, and curative rate.Results There were 98 patients enrolled in this study, with a mean age of 47.4 ± 11.4 years. All patients successfully underwent secondary FU therapy. Blisters developed among 16 (16.3%) patients, of whom 6 (6.1%) developed superficial skin ulcers. A curative response was observed among 46 (46.9%) patients, while an effective response was observed among 44 (44.9%) patients. Only 8 (8.2%) patients showed no improvement. The total response rate was 91.8%. A total of 12 (12.2%) cases recurred among all effective cases. Patients with a recurrence of NNEDV after more than 1.5 years following their first FU therapy demonstrated a higher response rate than those with a recurrence after less than 1.5 years.Conclusions A second FU therapy remains effective for patients with recurrent NNEDV with no obvious side effects. The response rate, however, is higher for patients who experience recurrence of NNDEDV after more than 1.5 years.https://www.tandfonline.com/doi/10.1080/02656736.2022.2131000Non-neoplastic epithelial disorders of the vulvafocused ultrasoundefficacyrecurrencesafety |
| spellingShingle | Ruizhen Li Jianfa Jiang The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva International Journal of Hyperthermia Non-neoplastic epithelial disorders of the vulva focused ultrasound efficacy recurrence safety |
| title | The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva |
| title_full | The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva |
| title_fullStr | The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva |
| title_full_unstemmed | The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva |
| title_short | The efficacy and safety of secondary focused ultrasound therapy for recurrence of non-neoplastic epithelial disorders of the vulva |
| title_sort | efficacy and safety of secondary focused ultrasound therapy for recurrence of non neoplastic epithelial disorders of the vulva |
| topic | Non-neoplastic epithelial disorders of the vulva focused ultrasound efficacy recurrence safety |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2022.2131000 |
| work_keys_str_mv | AT ruizhenli theefficacyandsafetyofsecondaryfocusedultrasoundtherapyforrecurrenceofnonneoplasticepithelialdisordersofthevulva AT jianfajiang theefficacyandsafetyofsecondaryfocusedultrasoundtherapyforrecurrenceofnonneoplasticepithelialdisordersofthevulva AT ruizhenli efficacyandsafetyofsecondaryfocusedultrasoundtherapyforrecurrenceofnonneoplasticepithelialdisordersofthevulva AT jianfajiang efficacyandsafetyofsecondaryfocusedultrasoundtherapyforrecurrenceofnonneoplasticepithelialdisordersofthevulva |