SARS-CoV-2 in the ocular surface of COVID-19 patients

Abstract The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surf...

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Main Authors: Hua-Tao Xie, Shi-Yun Jiang, Kang-Kang Xu, Xin Liu, Bing Xu, Lin Wang, Ming-Chang Zhang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Eye and Vision
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40662-020-00189-0
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author Hua-Tao Xie
Shi-Yun Jiang
Kang-Kang Xu
Xin Liu
Bing Xu
Lin Wang
Ming-Chang Zhang
author_facet Hua-Tao Xie
Shi-Yun Jiang
Kang-Kang Xu
Xin Liu
Bing Xu
Lin Wang
Ming-Chang Zhang
author_sort Hua-Tao Xie
collection DOAJ
description Abstract The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.
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spelling doaj.art-2daa233e9d8841aeb499c506a5ae4cde2022-12-22T03:54:25ZengBMCEye and Vision2326-02542020-04-01711310.1186/s40662-020-00189-0SARS-CoV-2 in the ocular surface of COVID-19 patientsHua-Tao Xie0Shi-Yun Jiang1Kang-Kang Xu2Xin Liu3Bing Xu4Lin Wang5Ming-Chang Zhang6Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Clinical Laboratory, Research Center for Tissue Engineering and Regenerative Medicine, Union Hospital, Huazhong University of Science and TechnologyDepartment of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyAbstract The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.http://link.springer.com/article/10.1186/s40662-020-00189-0SARS-CoV-2COVID-19Ocular surface
spellingShingle Hua-Tao Xie
Shi-Yun Jiang
Kang-Kang Xu
Xin Liu
Bing Xu
Lin Wang
Ming-Chang Zhang
SARS-CoV-2 in the ocular surface of COVID-19 patients
Eye and Vision
SARS-CoV-2
COVID-19
Ocular surface
title SARS-CoV-2 in the ocular surface of COVID-19 patients
title_full SARS-CoV-2 in the ocular surface of COVID-19 patients
title_fullStr SARS-CoV-2 in the ocular surface of COVID-19 patients
title_full_unstemmed SARS-CoV-2 in the ocular surface of COVID-19 patients
title_short SARS-CoV-2 in the ocular surface of COVID-19 patients
title_sort sars cov 2 in the ocular surface of covid 19 patients
topic SARS-CoV-2
COVID-19
Ocular surface
url http://link.springer.com/article/10.1186/s40662-020-00189-0
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AT xinliu sarscov2intheocularsurfaceofcovid19patients
AT bingxu sarscov2intheocularsurfaceofcovid19patients
AT linwang sarscov2intheocularsurfaceofcovid19patients
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