Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL Responsiveness

This article focuses on a stochastic viral model with distributed delay and CTL responsiveness. It is shown that the viral disease will be extinct if the stochastic reproductive ratio is less than one. However, when the stochastic reproductive ratio is more than one, the viral infection system consi...

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Main Authors: Jianguo Sun, Miaomiao Gao, Daqing Jiang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/8/766
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author Jianguo Sun
Miaomiao Gao
Daqing Jiang
author_facet Jianguo Sun
Miaomiao Gao
Daqing Jiang
author_sort Jianguo Sun
collection DOAJ
description This article focuses on a stochastic viral model with distributed delay and CTL responsiveness. It is shown that the viral disease will be extinct if the stochastic reproductive ratio is less than one. However, when the stochastic reproductive ratio is more than one, the viral infection system consists of an ergodic stationary distribution. Furthermore, we obtain the existence and uniqueness of the global positive solution by constructing a suitable Lyapunov function. Finally, we illustrate our results by numerical simulation.
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spelling doaj.art-2dafee15d89647118757e721b21984b62023-11-22T08:22:35ZengMDPI AGLife2075-17292021-07-0111876610.3390/life11080766Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL ResponsivenessJianguo Sun0Miaomiao Gao1Daqing Jiang2School of Science, China University of Petroleum (East China), Qingdao 266580, ChinaSchool of Science, China University of Petroleum (East China), Qingdao 266580, ChinaSchool of Science, China University of Petroleum (East China), Qingdao 266580, ChinaThis article focuses on a stochastic viral model with distributed delay and CTL responsiveness. It is shown that the viral disease will be extinct if the stochastic reproductive ratio is less than one. However, when the stochastic reproductive ratio is more than one, the viral infection system consists of an ergodic stationary distribution. Furthermore, we obtain the existence and uniqueness of the global positive solution by constructing a suitable Lyapunov function. Finally, we illustrate our results by numerical simulation.https://www.mdpi.com/2075-1729/11/8/766stochastic viral modeltime delayedCTL responsivenessergodic stationary distributionextinction
spellingShingle Jianguo Sun
Miaomiao Gao
Daqing Jiang
Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL Responsiveness
Life
stochastic viral model
time delayed
CTL responsiveness
ergodic stationary distribution
extinction
title Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL Responsiveness
title_full Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL Responsiveness
title_fullStr Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL Responsiveness
title_full_unstemmed Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL Responsiveness
title_short Threshold Dynamics of a Non-Linear Stochastic Viral Model with Time Delay and CTL Responsiveness
title_sort threshold dynamics of a non linear stochastic viral model with time delay and ctl responsiveness
topic stochastic viral model
time delayed
CTL responsiveness
ergodic stationary distribution
extinction
url https://www.mdpi.com/2075-1729/11/8/766
work_keys_str_mv AT jianguosun thresholddynamicsofanonlinearstochasticviralmodelwithtimedelayandctlresponsiveness
AT miaomiaogao thresholddynamicsofanonlinearstochasticviralmodelwithtimedelayandctlresponsiveness
AT daqingjiang thresholddynamicsofanonlinearstochasticviralmodelwithtimedelayandctlresponsiveness