PRRSV-1 induced lung lesion is associated with an imbalance between costimulatory and coinhibitory immune checkpoints

PRRSV-1 induced lung lesion is associated with an imbalance between costimulatory and coinhibitory immune checkpoints

Porcine reproductive and respiratory syndrome virus (PRRSV) induces a dysregulation on the innate and adaptive immune responses. T-cell activation requires a proper interaction and precise balance between costimulatory and coinhibitory molecules, commonly known as immune checkpoints. This study aims...

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Bibliographic Details
Main Authors: Inés Ruedas-Torres, José María Sánchez-Carvajal, Librado Carrasco, Francisco José Pallarés, Fernanda Larenas-Muñoz, Irene Magdalena Rodríguez-Gómez, Jaime Gómez-Laguna
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Microbiology
Subjects:
immune checkpoints
dysregulation
lung
lymph node
PRRSV
virulence
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1007523/full

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