Commensal microbiota contributes to chronic endocarditis in TAX1BP1 deficient mice.

Commensal microbiota contributes to chronic endocarditis in TAX1BP1 deficient mice.

Tax1-binding protein 1 (Tax1bp1) negatively regulates NF-κB by editing the ubiquitylation of target molecules by its catalytic partner A20. Genetically engineered TAX1BP1-deficient (KO) mice develop age-dependent inflammatory constitutions in multiple organs manifested as valvulitis or dermatitis an...

Full description

Bibliographic Details
Main Authors: Satoko Nakano, Emi Ikebe, Yoshiyuki Tsukamoto, Yan Wang, Takashi Matsumoto, Takahiro Mitsui, Takaaki Yahiro, Kunimitsu Inoue, Hiroaki Kawazato, Aiko Yasuda, Kanako Ito, Shigeo Yokoyama, Naohiko Takahashi, Mitsuo Hori, Tatsuo Shimada, Masatsugu Moriyama, Toshiaki Kubota, Katsushige Ono, Wataru Fujibuchi, Kuan-Teh Jeang, Hidekatsu Iha, Akira Nishizono
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3785488?pdf=render

Internet

http://europepmc.org/articles/PMC3785488?pdf=render

Similar Items