Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment
Background: The aim of the study was to examine the treatment outcome for patients with cardiovascular implantable electronic device (CIED) infections after extraction. Methods: Patients who underwent CIED extractions due to an infection at Karolinska University Hospital 2006–2015 were analyzed. Res...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-07-01
|
| Series: | Infectious Disease Reports |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2036-7449/13/3/59 |
| _version_ | 1797518951167557632 |
|---|---|
| author | Jonas Hörnsten Louise Axelsson Katarina Westling |
| author_facet | Jonas Hörnsten Louise Axelsson Katarina Westling |
| author_sort | Jonas Hörnsten |
| collection | DOAJ |
| description | Background: The aim of the study was to examine the treatment outcome for patients with cardiovascular implantable electronic device (CIED) infections after extraction. Methods: Patients who underwent CIED extractions due to an infection at Karolinska University Hospital 2006–2015 were analyzed. Results: In total, 165 patients were reviewed, 104 (63%) with pocket infection and 61 (37%) with systemic infection. Of the patients with systemic infection, 34 and 25 patients fulfilled the criteria for definite and possible endocarditis, respectively. Complications after extraction occurred only in one patient. Reimplantation was made after a mean of 9.5 days and performed in 81% of those with pocket infection and 44.3% in systemic infection. Infection with the new device occurred in 4.6%. The mean length of hospital stay for patients with pocket infection was 5.7 days, compared to 38.6 days in systemic infection. One-year mortality was 7.7% and 22.2% in pocket infection and systemic infection, respectively. Patients with <i>Staphylococcus aureus</i> infection had a higher mortality. Conclusions: In this study, the majority of the patients had a pocket CIED infection, with a short hospital stay. Patients with a systemic infection, and <i>S. aureus</i> etiology, had a prolonged hospital stay and a higher mortality. |
| first_indexed | 2024-03-10T07:36:33Z |
| format | Article |
| id | doaj.art-2db7bad79bb0454fa0c465a9a3cd9d9d |
| institution | Directory Open Access Journal |
| issn | 2036-7449 |
| language | English |
| last_indexed | 2024-03-10T07:36:33Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Infectious Disease Reports |
| spelling | doaj.art-2db7bad79bb0454fa0c465a9a3cd9d9d2023-11-22T13:23:00ZengMDPI AGInfectious Disease Reports2036-74492021-07-0113362763510.3390/idr13030059Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic TreatmentJonas Hörnsten0Louise Axelsson1Katarina Westling2Department of Cardiology, Karolinska University Hospital, 17176 Stockholm, SwedenDepartment of Medicine, Division of Infectious Diseases and Dermatology, Karolinska Institutet, 17177 Solna, SwedenDepartment of Medicine, Division of Infectious Diseases and Dermatology, Karolinska Institutet, 17177 Solna, SwedenBackground: The aim of the study was to examine the treatment outcome for patients with cardiovascular implantable electronic device (CIED) infections after extraction. Methods: Patients who underwent CIED extractions due to an infection at Karolinska University Hospital 2006–2015 were analyzed. Results: In total, 165 patients were reviewed, 104 (63%) with pocket infection and 61 (37%) with systemic infection. Of the patients with systemic infection, 34 and 25 patients fulfilled the criteria for definite and possible endocarditis, respectively. Complications after extraction occurred only in one patient. Reimplantation was made after a mean of 9.5 days and performed in 81% of those with pocket infection and 44.3% in systemic infection. Infection with the new device occurred in 4.6%. The mean length of hospital stay for patients with pocket infection was 5.7 days, compared to 38.6 days in systemic infection. One-year mortality was 7.7% and 22.2% in pocket infection and systemic infection, respectively. Patients with <i>Staphylococcus aureus</i> infection had a higher mortality. Conclusions: In this study, the majority of the patients had a pocket CIED infection, with a short hospital stay. Patients with a systemic infection, and <i>S. aureus</i> etiology, had a prolonged hospital stay and a higher mortality.https://www.mdpi.com/2036-7449/13/3/59CIED-infectionsextractionssepticemiaendocarditislong-term survival |
| spellingShingle | Jonas Hörnsten Louise Axelsson Katarina Westling Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment Infectious Disease Reports CIED-infections extractions septicemia endocarditis long-term survival |
| title | Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment |
| title_full | Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment |
| title_fullStr | Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment |
| title_full_unstemmed | Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment |
| title_short | Cardiac Implantable Electronic Device Infections; Long-Term Outcome after Extraction and Antibiotic Treatment |
| title_sort | cardiac implantable electronic device infections long term outcome after extraction and antibiotic treatment |
| topic | CIED-infections extractions septicemia endocarditis long-term survival |
| url | https://www.mdpi.com/2036-7449/13/3/59 |
| work_keys_str_mv | AT jonashornsten cardiacimplantableelectronicdeviceinfectionslongtermoutcomeafterextractionandantibiotictreatment AT louiseaxelsson cardiacimplantableelectronicdeviceinfectionslongtermoutcomeafterextractionandantibiotictreatment AT katarinawestling cardiacimplantableelectronicdeviceinfectionslongtermoutcomeafterextractionandantibiotictreatment |