Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia
Pre-leukaemic clones, together with the propensity to cause disease in mice, are characterized by appearing early in myeloid leukaemia and being found at relapse. Here, the authors identify clones in human samples and find that they are characterized by hierarchically organized genetic lesions, whic...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
Nature Portfolio
2016-08-01
|
| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/ncomms12475 |