Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population
Bosnia and Herzegovina is located in the South-Eastern Europe, characterized by numerous historical influences, massive migration processes and complex population structure. For that reason, the aim of this study is to provide an accurate and precise update of the population genetics data of al...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Sarajevo, Institute for Genetic Engineering and Biotechnology
2021-06-01
|
| Series: | Genetics & Applications |
| Subjects: | |
| Online Access: | https://genapp.ba/editions/index.php/journal/article/view/140 |
| _version_ | 1811185787362869248 |
|---|---|
| author | Naida Babić Jordamović Tamara Kojović Serkan Dogan Larisa Bešić Lana Salihefendić Rijad Konjhodžić Sabahudin Ćordić Vedrana Škaro Petar Projić Vesna Hadžiavdić Adna Ašić Damir Marjanović |
| author_facet | Naida Babić Jordamović Tamara Kojović Serkan Dogan Larisa Bešić Lana Salihefendić Rijad Konjhodžić Sabahudin Ćordić Vedrana Škaro Petar Projić Vesna Hadžiavdić Adna Ašić Damir Marjanović |
| author_sort | Naida Babić Jordamović |
| collection | DOAJ |
| description |
Bosnia and Herzegovina is located in the South-Eastern Europe, characterized by numerous historical influences, massive migration processes and complex population structure. For that reason, the aim of this study is to provide an accurate and precise update of the population genetics data of allele frequencies on 23 Y-STR loci in Bosnia and Herzegovina using larger sample size. For this purpose, 480 adult male individuals from the general population have been genotyped over 23 Y-STR loci contained in the PowerPlex Y23 system. Population genetics parameters have been calculated, namely allele and haplotype frequencies, gene and haplotype diversity, as well as Rst and P values for the assessment of interpopulation differences. The obtained results are in close agreement with previously published data for Bosnian-Herzegovinian population, as well as for local subpopulations. This study offers significantly increased resolution and information content, with 454 unique haplotypes. Population comparison reveals no statistically significant differences between the study population and 12 European populations used for comparison, as visualized through an MDS plot and neighbour-joining phylogenetic tree. This study offers representative data for local Y chromosomes that can be used for forensic applications, paternity and kinship testing, as well as for genealogical studies.
|
| first_indexed | 2024-04-11T13:35:13Z |
| format | Article |
| id | doaj.art-2dbc10c870e543189b445a3fe4817cc0 |
| institution | Directory Open Access Journal |
| issn | 2566-2937 2566-431X |
| language | English |
| last_indexed | 2024-04-11T13:35:13Z |
| publishDate | 2021-06-01 |
| publisher | University of Sarajevo, Institute for Genetic Engineering and Biotechnology |
| record_format | Article |
| series | Genetics & Applications |
| spelling | doaj.art-2dbc10c870e543189b445a3fe4817cc02022-12-22T04:21:29ZengUniversity of Sarajevo, Institute for Genetic Engineering and BiotechnologyGenetics & Applications2566-29372566-431X2021-06-015110.31383/ga.vol5iss1pp51-63Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian populationNaida Babić Jordamović0Tamara Kojović1Serkan Dogan2Larisa Bešić3Lana Salihefendić4Rijad Konjhodžić5Sabahudin Ćordić6Vedrana Škaro7Petar Projić8Vesna Hadžiavdić9Adna Ašić10Damir Marjanović11Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and HerzegovinaDepartment of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and HerzegovinaDepartment of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and HerzegovinaDepartment of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and HerzegovinaDepartment of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina; Alea Genetic Centre, Sarajevo, Bosnia and HerzegovinaAlea Genetic Centre, Sarajevo, Bosnia and HerzegovinaDepartment of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovinanstitute for Anthropological Research, Centre for Applied Bioanthropology, Molecular Anthropology Laboratory, Zagreb, Croatia; Genos Ltd, DNA Laboratory, Zagreb CroatiaInstitute for Anthropological Research, Centre for Applied Bioanthropology, Molecular Anthropology Laboratory, Zagreb, Croatia; Genos Ltd, DNA Laboratory, Zagreb CroatiaUniversity of Tuzla, Department of Biology, Tuzla, Bosnia and HerzegovinaDepartment of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and HerzegovinaDepartment of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina; Institute for Anthropological Research, Centre for Applied Bioanthropology, Molecular Anthropology Laboratory, Zagreb, Croatia Bosnia and Herzegovina is located in the South-Eastern Europe, characterized by numerous historical influences, massive migration processes and complex population structure. For that reason, the aim of this study is to provide an accurate and precise update of the population genetics data of allele frequencies on 23 Y-STR loci in Bosnia and Herzegovina using larger sample size. For this purpose, 480 adult male individuals from the general population have been genotyped over 23 Y-STR loci contained in the PowerPlex Y23 system. Population genetics parameters have been calculated, namely allele and haplotype frequencies, gene and haplotype diversity, as well as Rst and P values for the assessment of interpopulation differences. The obtained results are in close agreement with previously published data for Bosnian-Herzegovinian population, as well as for local subpopulations. This study offers significantly increased resolution and information content, with 454 unique haplotypes. Population comparison reveals no statistically significant differences between the study population and 12 European populations used for comparison, as visualized through an MDS plot and neighbour-joining phylogenetic tree. This study offers representative data for local Y chromosomes that can be used for forensic applications, paternity and kinship testing, as well as for genealogical studies. https://genapp.ba/editions/index.php/journal/article/view/140Y chromosomeY-STRBosnia and HerzegovinaPowerPlex Y23 systempopulation genetics |
| spellingShingle | Naida Babić Jordamović Tamara Kojović Serkan Dogan Larisa Bešić Lana Salihefendić Rijad Konjhodžić Sabahudin Ćordić Vedrana Škaro Petar Projić Vesna Hadžiavdić Adna Ašić Damir Marjanović Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population Genetics & Applications Y chromosome Y-STR Bosnia and Herzegovina PowerPlex Y23 system population genetics |
| title | Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population |
| title_full | Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population |
| title_fullStr | Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population |
| title_full_unstemmed | Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population |
| title_short | Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population |
| title_sort | contemporary population genetics data for 23 y str loci in the general bosnian herzegovinian population |
| topic | Y chromosome Y-STR Bosnia and Herzegovina PowerPlex Y23 system population genetics |
| url | https://genapp.ba/editions/index.php/journal/article/view/140 |
| work_keys_str_mv | AT naidababicjordamovic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT tamarakojovic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT serkandogan contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT larisabesic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT lanasalihefendic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT rijadkonjhodzic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT sabahudincordic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT vedranaskaro contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT petarprojic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT vesnahadziavdic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT adnaasic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation AT damirmarjanovic contemporarypopulationgeneticsdatafor23ystrlociinthegeneralbosnianherzegovinianpopulation |