Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals
Abstract Background Recent studies have revealed some conflicting results about the health effects of caffeine. These studies are inconsistent in terms of design and population and source of consumed caffeine. In the current study, we aimed to evaluate the possible health effects of dietary caffeine...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Endocrine Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12902-023-01477-1 |
| _version_ | 1797559074870525952 |
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| author | Shadia Hamoud Alshahrani Yasir A. Atia Raheem Atiya Badir Sami G. Almalki Nahla A Tayyib Sana Shahab Rosario Mireya Romero-Parra Mohammed Kadhem Abid Beneen M. Hussien Pushpamala Ramaiah |
| author_facet | Shadia Hamoud Alshahrani Yasir A. Atia Raheem Atiya Badir Sami G. Almalki Nahla A Tayyib Sana Shahab Rosario Mireya Romero-Parra Mohammed Kadhem Abid Beneen M. Hussien Pushpamala Ramaiah |
| author_sort | Shadia Hamoud Alshahrani |
| collection | DOAJ |
| description | Abstract Background Recent studies have revealed some conflicting results about the health effects of caffeine. These studies are inconsistent in terms of design and population and source of consumed caffeine. In the current study, we aimed to evaluate the possible health effects of dietary caffeine intake among overweight and obese individuals. Methods In this cross-sectional study, 488 apparently healthy individuals with overweight and obesity were participated. Dietary intake was assessed by a Food Frequency Questionnaire (FFQ) and the amount of dietary caffeine was calculated. Body composition was determined by bioelectrical impedance analysis (BIA). Enzymatic methods were used to evaluate serum lipid, glucose, and insulin concentrations. Results Those at the highest tertile of dietary caffeine intake had lower percentage of fat mass, higher fat free mass and appetite score (P < 0.05). Also, lower total cholesterol (TC) and low density lipoprotein cholesterol (LDL-c) was observed in higher tertiles of dietary caffeine intake compared with lower tertiles. In multinomial adjusted models, those at the second tertile of dietary caffeine intake were more likely to have higher serum insulin (P = 0.04) and lower homeostatic model assessment of insulin resistance (HOMA-IR) values compared with first tertile (P = 0.03) in crude model. While, in the age, body mass index (BMI), sex, physical activity, socio-economic status (SES) and energy intake –adjusted model (Model III), those at the third tertile of dietary caffeine intake were more likely to have low serum LDL concentrations [odds ratio (OR) = 0.957; CI = 0.918–0.997; P = 0.04]. With further adjustment to dietary vegetable, fiber and grain intake, those at the third tertile of dietary caffeine intake were more likely to have low systolic blood pressure (SBP), LDL and high HDL levels compared with those at the first tertile (P < 0.05). Conclusion High intakes of dietary caffeine was associated with lower LDL, SBP, insulin resistance and higher HDL concentrations among overweight and obese individuals. However, due to observational design of the study, causal inference is impossible and further studies are warranted to confirm our findings. |
| first_indexed | 2024-03-10T17:40:33Z |
| format | Article |
| id | doaj.art-2dbcc96e9def4df3a8efcb032e475e7e |
| institution | Directory Open Access Journal |
| issn | 1472-6823 |
| language | English |
| last_indexed | 2024-03-10T17:40:33Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Endocrine Disorders |
| spelling | doaj.art-2dbcc96e9def4df3a8efcb032e475e7e2023-11-20T09:42:17ZengBMCBMC Endocrine Disorders1472-68232023-10-0123111010.1186/s12902-023-01477-1Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individualsShadia Hamoud Alshahrani0Yasir A. Atia1Raheem Atiya Badir2Sami G. Almalki3Nahla A Tayyib4Sana Shahab5Rosario Mireya Romero-Parra6Mohammed Kadhem Abid7Beneen M. Hussien8Pushpamala Ramaiah9Medical Surgical Nursing Department, King Khalid UniversityDepartment of Medical Chemistry, Al-Kindy College of Medicine, University of Baghdad, University of BaghdadCollege of Nursing, Al-Bayan UniversityDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah UniversityVice Deanship, Postgraduate Research and Scientific Studies, Faculty of Nursing, Umm Al-Qura UniversityDepartment of Business Administration, College of Business Administration, Princess Nourah bint Abdulrahman UniversityDepartment of General Studies, Universidad Continental. Lima, Universidad ContinentalDepartment of Anesthesia, College of Health & medical Technology, Al-Ayen UniversityMedical Laboratory Technology Department, College of Medical Technology, The Islamic UniversityFaculty of Nursing, Umm al- Qura UniversityAbstract Background Recent studies have revealed some conflicting results about the health effects of caffeine. These studies are inconsistent in terms of design and population and source of consumed caffeine. In the current study, we aimed to evaluate the possible health effects of dietary caffeine intake among overweight and obese individuals. Methods In this cross-sectional study, 488 apparently healthy individuals with overweight and obesity were participated. Dietary intake was assessed by a Food Frequency Questionnaire (FFQ) and the amount of dietary caffeine was calculated. Body composition was determined by bioelectrical impedance analysis (BIA). Enzymatic methods were used to evaluate serum lipid, glucose, and insulin concentrations. Results Those at the highest tertile of dietary caffeine intake had lower percentage of fat mass, higher fat free mass and appetite score (P < 0.05). Also, lower total cholesterol (TC) and low density lipoprotein cholesterol (LDL-c) was observed in higher tertiles of dietary caffeine intake compared with lower tertiles. In multinomial adjusted models, those at the second tertile of dietary caffeine intake were more likely to have higher serum insulin (P = 0.04) and lower homeostatic model assessment of insulin resistance (HOMA-IR) values compared with first tertile (P = 0.03) in crude model. While, in the age, body mass index (BMI), sex, physical activity, socio-economic status (SES) and energy intake –adjusted model (Model III), those at the third tertile of dietary caffeine intake were more likely to have low serum LDL concentrations [odds ratio (OR) = 0.957; CI = 0.918–0.997; P = 0.04]. With further adjustment to dietary vegetable, fiber and grain intake, those at the third tertile of dietary caffeine intake were more likely to have low systolic blood pressure (SBP), LDL and high HDL levels compared with those at the first tertile (P < 0.05). Conclusion High intakes of dietary caffeine was associated with lower LDL, SBP, insulin resistance and higher HDL concentrations among overweight and obese individuals. However, due to observational design of the study, causal inference is impossible and further studies are warranted to confirm our findings.https://doi.org/10.1186/s12902-023-01477-1Dietary caffeine intakeObesityOverweightMetabolic parametersGlycemic status |
| spellingShingle | Shadia Hamoud Alshahrani Yasir A. Atia Raheem Atiya Badir Sami G. Almalki Nahla A Tayyib Sana Shahab Rosario Mireya Romero-Parra Mohammed Kadhem Abid Beneen M. Hussien Pushpamala Ramaiah Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals BMC Endocrine Disorders Dietary caffeine intake Obesity Overweight Metabolic parameters Glycemic status |
| title | Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals |
| title_full | Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals |
| title_fullStr | Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals |
| title_full_unstemmed | Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals |
| title_short | Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals |
| title_sort | dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals |
| topic | Dietary caffeine intake Obesity Overweight Metabolic parameters Glycemic status |
| url | https://doi.org/10.1186/s12902-023-01477-1 |
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