Transcriptome analysis of Burkitt lymphoma cells treated with anti-convulsant drugs that are inhibitors of Epstein-Barr virus lytic reactivation.

Transcriptome analysis of Burkitt lymphoma cells treated with anti-convulsant drugs that are inhibitors of Epstein-Barr virus lytic reactivation.

Herpesviruses have two distinct life cycle stages, latency and lytic replication. Epstein-Barr virus (EBV), a gamma-herpesvirus, establishes latency in vivo and in cultured cells. Cell lines harboring latent EBV can be induced into the lytic cycle by treatment with chemical inducing agents. In the B...

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Detalles Bibliográficos
Main Authors: Kelly L Gorres, David M Reineke, George Miller
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Acceso en liña:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299198&type=printable

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