Transcriptome analysis of Burkitt lymphoma cells treated with anti-convulsant drugs that are inhibitors of Epstein-Barr virus lytic reactivation.

Herpesviruses have two distinct life cycle stages, latency and lytic replication. Epstein-Barr virus (EBV), a gamma-herpesvirus, establishes latency in vivo and in cultured cells. Cell lines harboring latent EBV can be induced into the lytic cycle by treatment with chemical inducing agents. In the B...

Description complète

Détails bibliographiques
Auteurs principaux: Kelly L Gorres, David M Reineke, George Miller
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2024-01-01
Collection:PLoS ONE
Accès en ligne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299198&type=printable