Antioxidant capacity of sesamol in Caenorhabditis elegans model system
Abstract Senescence is a general and irreversible process which depends on both inherent (free radical and age) and external (Ultraviolet irradiation) factors. Antioxidants and other natural compounds like plant and plant products are widespread use for their medicinal and therapeutic values. The pr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | Food Production, Processing and Nutrition |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43014-023-00186-5 |
| _version_ | 1797363041473396736 |
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| author | Jinian Huang Shuning Qi Qiang Sun Guohui Song Jixing Tang Yuquan Duan |
| author_facet | Jinian Huang Shuning Qi Qiang Sun Guohui Song Jixing Tang Yuquan Duan |
| author_sort | Jinian Huang |
| collection | DOAJ |
| description | Abstract Senescence is a general and irreversible process which depends on both inherent (free radical and age) and external (Ultraviolet irradiation) factors. Antioxidants and other natural compounds like plant and plant products are widespread use for their medicinal and therapeutic values. The present study focuses on the role of sesamol which has been used to delay the effects of photoaging using model nematode Caenorhabditis elegans (C. elegan) by measuring the longest life, average life, reproductive capacity, and the variation of reactive oxygen of C. elegans under different stress conditions. The result showed that 200 µg·mL−1 sesamol significantly extended the life of C. elegans, that is, the mean lifespan of the treatment groups were 43.3% longer than control group. Meanwhile, sesamol significantly prolonged the lifespan of C. elegans under heat stress, ultraviolet irradiation stress, and oxidative stress. Above all, sesamol could be used as potential antioxidant compounds which will be of greater significance for health-based research. Graphical Abstract |
| first_indexed | 2024-03-08T16:15:04Z |
| format | Article |
| id | doaj.art-2dc8db62184a49128a4f84b3ca797be9 |
| institution | Directory Open Access Journal |
| issn | 2661-8974 |
| language | English |
| last_indexed | 2024-03-08T16:15:04Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Food Production, Processing and Nutrition |
| spelling | doaj.art-2dc8db62184a49128a4f84b3ca797be92024-01-07T12:37:04ZengBMCFood Production, Processing and Nutrition2661-89742024-01-016111010.1186/s43014-023-00186-5Antioxidant capacity of sesamol in Caenorhabditis elegans model systemJinian Huang0Shuning Qi1Qiang Sun2Guohui Song3Jixing Tang4Yuquan Duan5Institute of Agricultural and Byproduct Processing, Henan Academy of Agricultural SciencesInstitute of Food Science and Technology, Chinese Academy of Agricultural SciencesInstitute of Agricultural and Byproduct Processing, Henan Academy of Agricultural SciencesInstitute of Agricultural and Byproduct Processing, Henan Academy of Agricultural SciencesInstitute of Food Science and Technology, Chinese Academy of Agricultural SciencesInstitute of Food Science and Technology, Chinese Academy of Agricultural SciencesAbstract Senescence is a general and irreversible process which depends on both inherent (free radical and age) and external (Ultraviolet irradiation) factors. Antioxidants and other natural compounds like plant and plant products are widespread use for their medicinal and therapeutic values. The present study focuses on the role of sesamol which has been used to delay the effects of photoaging using model nematode Caenorhabditis elegans (C. elegan) by measuring the longest life, average life, reproductive capacity, and the variation of reactive oxygen of C. elegans under different stress conditions. The result showed that 200 µg·mL−1 sesamol significantly extended the life of C. elegans, that is, the mean lifespan of the treatment groups were 43.3% longer than control group. Meanwhile, sesamol significantly prolonged the lifespan of C. elegans under heat stress, ultraviolet irradiation stress, and oxidative stress. Above all, sesamol could be used as potential antioxidant compounds which will be of greater significance for health-based research. Graphical Abstracthttps://doi.org/10.1186/s43014-023-00186-5SesamolAntioxidantLifespanReactive oxygen speciesCaenorhabditis elegans |
| spellingShingle | Jinian Huang Shuning Qi Qiang Sun Guohui Song Jixing Tang Yuquan Duan Antioxidant capacity of sesamol in Caenorhabditis elegans model system Food Production, Processing and Nutrition Sesamol Antioxidant Lifespan Reactive oxygen species Caenorhabditis elegans |
| title | Antioxidant capacity of sesamol in Caenorhabditis elegans model system |
| title_full | Antioxidant capacity of sesamol in Caenorhabditis elegans model system |
| title_fullStr | Antioxidant capacity of sesamol in Caenorhabditis elegans model system |
| title_full_unstemmed | Antioxidant capacity of sesamol in Caenorhabditis elegans model system |
| title_short | Antioxidant capacity of sesamol in Caenorhabditis elegans model system |
| title_sort | antioxidant capacity of sesamol in caenorhabditis elegans model system |
| topic | Sesamol Antioxidant Lifespan Reactive oxygen species Caenorhabditis elegans |
| url | https://doi.org/10.1186/s43014-023-00186-5 |
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