Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model
Monitoring cerebral circulation during cardiopulmonary resuscitation (CPR) is essential to improve patients’ prognosis and quality of life. We assessed the feasibility of non-invasive electroencephalography (EEG) parameters as predictive factors of cerebral resuscitation in a ventricular fibrillatio...
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MDPI AG
2020-05-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/11/3052 |
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| author | Heejin Kim Ki Hong Kim Ki Jeong Hong Yunseo Ku Sang Do Shin Hee Chan Kim |
| author_facet | Heejin Kim Ki Hong Kim Ki Jeong Hong Yunseo Ku Sang Do Shin Hee Chan Kim |
| author_sort | Heejin Kim |
| collection | DOAJ |
| description | Monitoring cerebral circulation during cardiopulmonary resuscitation (CPR) is essential to improve patients’ prognosis and quality of life. We assessed the feasibility of non-invasive electroencephalography (EEG) parameters as predictive factors of cerebral resuscitation in a ventricular fibrillation (VF) swine model. After 1 min untreated VF, four cycles of basic life support were performed and the first defibrillation was administered. Sustained return of spontaneous circulation (ROSC) was confirmed if a palpable pulse persisted for 20 min. Otherwise, one cycle of advanced cardiovascular life support (ACLS) and defibrillation were administered immediately. Successfully defibrillated animals were continuously monitored. If sustained ROSC was not achieved, another cycle of ACLS was administered. Non-ROSC was confirmed when sustained ROSC did not occur after 10 ACLS cycles. EEG and hemodynamic parameters were measured during experiments. Data measured for approximately 3 s right before the defibrillation attempts were analyzed to investigate the relationship between the recovery of carotid blood flow (CBF) and non-invasive EEG parameters, including time- and frequency-domain parameters and entropy indices. We found that time-domain magnitude and entropy measures of EEG correlated with the change of CBF. Further studies are warranted to evaluate these EEG parameters as potential markers of cerebral circulation during CPR. |
| first_indexed | 2024-03-10T19:32:29Z |
| format | Article |
| id | doaj.art-2dc929fbce244356b7cc7fd80641f41c |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T19:32:29Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-2dc929fbce244356b7cc7fd80641f41c2023-11-20T02:00:07ZengMDPI AGSensors1424-82202020-05-012011305210.3390/s20113052Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine ModelHeejin Kim0Ki Hong Kim1Ki Jeong Hong2Yunseo Ku3Sang Do Shin4Hee Chan Kim5Interdisciplinary Program in Bioengineering, Graduate School, Seoul National University, Seoul 03080, KoreaDepartment of Emergency Medicine, Seoul National University Hospital, Seoul 03080, KoreaDepartment of Emergency Medicine, Seoul National University Hospital, Seoul 03080, KoreaDepartment of Biomedical Engineering, Chungnam National University College of Medicine, 266, Munwha-ro, Jung-gu, Deajeon 35015, KoreaDepartment of Emergency Medicine, Seoul National University Hospital, Seoul 03080, KoreaDepartment of Biomedical Engineering, Seoul National University College of Medicine, Seoul 03080, KoreaMonitoring cerebral circulation during cardiopulmonary resuscitation (CPR) is essential to improve patients’ prognosis and quality of life. We assessed the feasibility of non-invasive electroencephalography (EEG) parameters as predictive factors of cerebral resuscitation in a ventricular fibrillation (VF) swine model. After 1 min untreated VF, four cycles of basic life support were performed and the first defibrillation was administered. Sustained return of spontaneous circulation (ROSC) was confirmed if a palpable pulse persisted for 20 min. Otherwise, one cycle of advanced cardiovascular life support (ACLS) and defibrillation were administered immediately. Successfully defibrillated animals were continuously monitored. If sustained ROSC was not achieved, another cycle of ACLS was administered. Non-ROSC was confirmed when sustained ROSC did not occur after 10 ACLS cycles. EEG and hemodynamic parameters were measured during experiments. Data measured for approximately 3 s right before the defibrillation attempts were analyzed to investigate the relationship between the recovery of carotid blood flow (CBF) and non-invasive EEG parameters, including time- and frequency-domain parameters and entropy indices. We found that time-domain magnitude and entropy measures of EEG correlated with the change of CBF. Further studies are warranted to evaluate these EEG parameters as potential markers of cerebral circulation during CPR.https://www.mdpi.com/1424-8220/20/11/3052cardiopulmonary resuscitation (CPR)electroencephalogram (EEG)hemodynamic datacarotid blood flow (CBF)cerebral circulation |
| spellingShingle | Heejin Kim Ki Hong Kim Ki Jeong Hong Yunseo Ku Sang Do Shin Hee Chan Kim Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model Sensors cardiopulmonary resuscitation (CPR) electroencephalogram (EEG) hemodynamic data carotid blood flow (CBF) cerebral circulation |
| title | Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model |
| title_full | Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model |
| title_fullStr | Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model |
| title_full_unstemmed | Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model |
| title_short | Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model |
| title_sort | frontal eeg changes with the recovery of carotid blood flow in a cardiac arrest swine model |
| topic | cardiopulmonary resuscitation (CPR) electroencephalogram (EEG) hemodynamic data carotid blood flow (CBF) cerebral circulation |
| url | https://www.mdpi.com/1424-8220/20/11/3052 |
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