Application of Silver Nanoparticles in Parasite Treatment
Silver nanoparticles (AgNPs) are ultra-small silver particles with a size from 1 to 100 nanometers. Unlike bulk silver, they have unique physical and chemical properties. Numerous studies have shown that AgNPs have beneficial biological effects on various diseases, including antibacterial, anti-infl...
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| Format: | Article |
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MDPI AG
2023-06-01
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| Series: | Pharmaceutics |
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| Online Access: | https://www.mdpi.com/1999-4923/15/7/1783 |
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| author | Ping Zhang Jiahao Gong Yan Jiang Yunfeng Long Weiqiang Lei Xiuge Gao Dawei Guo |
| author_facet | Ping Zhang Jiahao Gong Yan Jiang Yunfeng Long Weiqiang Lei Xiuge Gao Dawei Guo |
| author_sort | Ping Zhang |
| collection | DOAJ |
| description | Silver nanoparticles (AgNPs) are ultra-small silver particles with a size from 1 to 100 nanometers. Unlike bulk silver, they have unique physical and chemical properties. Numerous studies have shown that AgNPs have beneficial biological effects on various diseases, including antibacterial, anti-inflammatory, antioxidant, antiparasitic, and antiviruses. One of the most well-known applications is in the field of antibacterial applications, where AgNPs have strong abilities to kill multi-drug resistant bacteria, making them a potential candidate as an antibacterial drug. Recently, AgNPs synthesized from plant extracts have exhibited outstanding antiparasitic effects, with a shorter duration of use and enhanced ability to inhibit parasite multiplication compared to traditional antiparasitic drugs. This review summarizes the types, characteristics, and the mechanism of action of AgNPs in anti-parasitism, mainly focusing on their effects in leishmaniasis, flukes, cryptosporidiosis, toxoplasmosis, <i>Haemonchus</i>, <i>Blastocystis hominis</i>, and <i>Strongylides</i>. The aim is to provide a reference for the application of AgNPs in the prevention and control of parasitic diseases. |
| first_indexed | 2024-03-11T00:44:39Z |
| format | Article |
| id | doaj.art-2dcad7289baa4522b384809ce03c0329 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-11T00:44:39Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-2dcad7289baa4522b384809ce03c03292023-11-18T20:53:46ZengMDPI AGPharmaceutics1999-49232023-06-01157178310.3390/pharmaceutics15071783Application of Silver Nanoparticles in Parasite TreatmentPing Zhang0Jiahao Gong1Yan Jiang2Yunfeng Long3Weiqiang Lei4Xiuge Gao5Dawei Guo6College of Animal Science and Food Engineering, Jinling Institute of Technology, 99 Hongjing Road, Nanjing 211169, ChinaEngineering Center of Innovative Veterinary Drugs, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, ChinaAnimal, Plant and Food Inspection Center of Nanjing Customs District, 39 Chuangzhi Road, Nanjing 210000, ChinaAnimal, Plant and Food Inspection Center of Nanjing Customs District, 39 Chuangzhi Road, Nanjing 210000, ChinaCollege of Animal Science and Food Engineering, Jinling Institute of Technology, 99 Hongjing Road, Nanjing 211169, ChinaEngineering Center of Innovative Veterinary Drugs, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, ChinaEngineering Center of Innovative Veterinary Drugs, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, ChinaSilver nanoparticles (AgNPs) are ultra-small silver particles with a size from 1 to 100 nanometers. Unlike bulk silver, they have unique physical and chemical properties. Numerous studies have shown that AgNPs have beneficial biological effects on various diseases, including antibacterial, anti-inflammatory, antioxidant, antiparasitic, and antiviruses. One of the most well-known applications is in the field of antibacterial applications, where AgNPs have strong abilities to kill multi-drug resistant bacteria, making them a potential candidate as an antibacterial drug. Recently, AgNPs synthesized from plant extracts have exhibited outstanding antiparasitic effects, with a shorter duration of use and enhanced ability to inhibit parasite multiplication compared to traditional antiparasitic drugs. This review summarizes the types, characteristics, and the mechanism of action of AgNPs in anti-parasitism, mainly focusing on their effects in leishmaniasis, flukes, cryptosporidiosis, toxoplasmosis, <i>Haemonchus</i>, <i>Blastocystis hominis</i>, and <i>Strongylides</i>. The aim is to provide a reference for the application of AgNPs in the prevention and control of parasitic diseases.https://www.mdpi.com/1999-4923/15/7/1783silver nanomaterialsapplicationparasitic diseases |
| spellingShingle | Ping Zhang Jiahao Gong Yan Jiang Yunfeng Long Weiqiang Lei Xiuge Gao Dawei Guo Application of Silver Nanoparticles in Parasite Treatment Pharmaceutics silver nanomaterials application parasitic diseases |
| title | Application of Silver Nanoparticles in Parasite Treatment |
| title_full | Application of Silver Nanoparticles in Parasite Treatment |
| title_fullStr | Application of Silver Nanoparticles in Parasite Treatment |
| title_full_unstemmed | Application of Silver Nanoparticles in Parasite Treatment |
| title_short | Application of Silver Nanoparticles in Parasite Treatment |
| title_sort | application of silver nanoparticles in parasite treatment |
| topic | silver nanomaterials application parasitic diseases |
| url | https://www.mdpi.com/1999-4923/15/7/1783 |
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