Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma
Intraoperative tumor thrombus embolization is a potentially lethal complication during inferior vena cava (IVC) thrombectomy for renal cell carcinoma (RCC). Intraoperative embolization is uncommonly encountered because IVC thrombectomy surgical technique is focused on avoiding this complication. No...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Codon Publications
2023-12-01
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| Series: | Journal of Kidney Cancer and VHL |
| Subjects: | |
| Online Access: | https://jkcvhl.com/index.php/jkcvhl/article/view/299 |
| _version_ | 1827147930867335168 |
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| author | Samantha A. Roberts Divyaam Satija Henry Gold Mina S. Makary Jing G. Wang Eric A. Singer Tasha Posid Nahush A. Mokadam Shawn Dason |
| author_facet | Samantha A. Roberts Divyaam Satija Henry Gold Mina S. Makary Jing G. Wang Eric A. Singer Tasha Posid Nahush A. Mokadam Shawn Dason |
| author_sort | Samantha A. Roberts |
| collection | DOAJ |
| description |
Intraoperative tumor thrombus embolization is a potentially lethal complication during inferior vena cava (IVC) thrombectomy for renal cell carcinoma (RCC). Intraoperative embolization is uncommonly encountered because IVC thrombectomy surgical technique is focused on avoiding this complication. Nonetheless, early recognition of embolization is essential so that emergent management can be instituted. When available, cardiopulmonary bypass (CPB) and embolectomy should be considered the gold standard for the management of intraoperative embolization. Several novel endovascular techniques are also available for selective use. We present the case of a 71-year-old female with a right renal mass and level II (retrohepatic) IVC tumor thrombus. During cytoreductive nephrectomy and IVC thrombectomy, tumor embolization was diagnosed during a period of hypotension based on transesophageal echocardiographic finding of new thrombus within the right atrium. This prompted sternotomy, CPB, and pulmonary artery embolectomy. The patient survived this embolization event and has a complete response to systemic therapy 9 months postoperatively. This case serves as the framework for a discussion on management considerations surrounding intraoperative embolization during IVC thrombectomy.
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| first_indexed | 2024-03-07T14:02:47Z |
| format | Article |
| id | doaj.art-2dcb247f2b4b4081bd897331c2c5cef6 |
| institution | Directory Open Access Journal |
| issn | 2203-5826 |
| language | English |
| last_indexed | 2025-03-20T20:54:13Z |
| publishDate | 2023-12-01 |
| publisher | Codon Publications |
| record_format | Article |
| series | Journal of Kidney Cancer and VHL |
| spelling | doaj.art-2dcb247f2b4b4081bd897331c2c5cef62024-08-14T07:17:20ZengCodon PublicationsJournal of Kidney Cancer and VHL2203-58262023-12-0110410.15586/jkcvhl.v10i4.299Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell CarcinomaSamantha A. Roberts0Divyaam Satija1Henry Gold2Mina S. Makary3Jing G. Wang4Eric A. Singer5Tasha Posid6Nahush A. Mokadam7Shawn Dason8Division of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH; Wright State University Boonshoft School of Medicine, Dayton, OH.Division of Cardiac Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.Division of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH.Division of Vascular and Interventional Radiology, Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH.Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.Division of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH.Division of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH.Division of Cardiac Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.Division of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH. Intraoperative tumor thrombus embolization is a potentially lethal complication during inferior vena cava (IVC) thrombectomy for renal cell carcinoma (RCC). Intraoperative embolization is uncommonly encountered because IVC thrombectomy surgical technique is focused on avoiding this complication. Nonetheless, early recognition of embolization is essential so that emergent management can be instituted. When available, cardiopulmonary bypass (CPB) and embolectomy should be considered the gold standard for the management of intraoperative embolization. Several novel endovascular techniques are also available for selective use. We present the case of a 71-year-old female with a right renal mass and level II (retrohepatic) IVC tumor thrombus. During cytoreductive nephrectomy and IVC thrombectomy, tumor embolization was diagnosed during a period of hypotension based on transesophageal echocardiographic finding of new thrombus within the right atrium. This prompted sternotomy, CPB, and pulmonary artery embolectomy. The patient survived this embolization event and has a complete response to systemic therapy 9 months postoperatively. This case serves as the framework for a discussion on management considerations surrounding intraoperative embolization during IVC thrombectomy. https://jkcvhl.com/index.php/jkcvhl/article/view/299embolizationintraoperativeRCCthrombectomytumor |
| spellingShingle | Samantha A. Roberts Divyaam Satija Henry Gold Mina S. Makary Jing G. Wang Eric A. Singer Tasha Posid Nahush A. Mokadam Shawn Dason Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma Journal of Kidney Cancer and VHL embolization intraoperative RCC thrombectomy tumor |
| title | Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma |
| title_full | Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma |
| title_fullStr | Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma |
| title_full_unstemmed | Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma |
| title_short | Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma |
| title_sort | intraoperative embolization during inferior vena cava tumor thrombectomy for renal cell carcinoma |
| topic | embolization intraoperative RCC thrombectomy tumor |
| url | https://jkcvhl.com/index.php/jkcvhl/article/view/299 |
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