Loss of MAPK8IP3 Affects Endocytosis in Neurons
Perturbations in endo-lysosomal trafficking pathways are linked to many neurodevelopmental and neurodegenerative diseases. Of relevance to our current study, MAPK8IP3/JIP3, a brain enriched putative adaptor between lysosomes and motors has been previously implicated as a key regulator of axonal lyso...
Main Authors: | Amanda M. Snead, Swetha Gowrishankar |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-05-01
|
Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fncel.2022.828071/full |
Similar Items
-
Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons [version 1; peer review: 3 approved]
by: Nicholas D. Allen, et al.
Published: (2020-05-01) -
An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
by: María José Castellanos-Montiel, et al.
Published: (2023-02-01) -
CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks
by: Eric Deneault, et al.
Published: (2019-02-01) -
Deficiency of the Lysosomal Protein CLN5 Alters Lysosomal Function and Movement
by: Indranil Basak, et al.
Published: (2021-09-01) -
Mitochondrial Phenotypes in Parkinson’s Diseases—A Focus on Human iPSC-Derived Dopaminergic Neurons
by: Leonie M. Heger, et al.
Published: (2021-12-01)