Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.

Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.

Signaling by the Notch ligands Delta (Dl) and Serrate (Ser) regulates a wide variety of essential cell-fate decisions during animal development. Two distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (Mib), have been shown to regulate Dl signaling in Drosophila melanogaster and Danio rer...

Full description

Bibliographic Details
Main Authors: Roland Le Borgne, Sylvie Remaud, Sophie Hamel, François Schweisguth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1064853?pdf=render

Similar Items

Similar Items