Suppressive regulatory T cells and latent transforming growth factor-β-expressing macrophages are altered in the peritoneal fluid of patients with endometriosis

Suppressive regulatory T cells and latent transforming growth factor-β-expressing macrophages are altered in the peritoneal fluid of patients with endometriosis

Abstract Background Endometriosis is a known cause of infertility. Differences in immune tolerance caused by regulatory T cells (Tregs) and transforming growth factor-β (TGF-β) are thought to be involved in the pathology of endometriosis. Evidence has indicated that Tregs can be separated into three...

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Bibliographic Details
Main Authors: Tetsuro Hanada, Shunichiro Tsuji, Misako Nakayama, Shiro Wakinoue, Kyoko Kasahara, Fuminori Kimura, Takahide Mori, Kazumasa Ogasawara, Takashi Murakami
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Reproductive Biology and Endocrinology
Subjects:
Regulatory T cell
TGF-β
Latency-associated peptide
Endometriosis
Online Access:http://link.springer.com/article/10.1186/s12958-018-0325-2

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