OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2
Abstract. Flow cytometry allows estimating quantitative and qualitative structure of populations and subpopulations of immune system cells by using various methodical approaches and a wide spectrum of reagents. For diagnostics the Acquired Immune Deficiency Syndrome (AIDS) caused by a Human Immunode...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Sankt-Peterburg : NIIÈM imeni Pastera
2014-06-01
|
| Series: | Инфекция и иммунитет |
| Subjects: | |
| Online Access: | https://www.iimmun.ru/iimm/article/view/35 |
| _version_ | 1797972502446604288 |
|---|---|
| author | S. V. Khaidukov A. V. Zurochka |
| author_facet | S. V. Khaidukov A. V. Zurochka |
| author_sort | S. V. Khaidukov |
| collection | DOAJ |
| description | Abstract. Flow cytometry allows estimating quantitative and qualitative structure of populations and subpopulations of immune system cells by using various methodical approaches and a wide spectrum of reagents. For diagnostics the Acquired Immune Deficiency Syndrome (AIDS) caused by a Human Immunodeficiency Virus (HIV) the flow cytometry became irreplaceable. Traditionally, immunologists examine standard model of an estimation of immune dysfunction on the basis of classical markers of Т-cells (CD3, CD4, CD8) at the HIV-infection. But researchers pay less attention to other populations and subpopulations of lymphocytes, such as γδ-, αβ- and CD38+ Т-cells. The quantitative estimation of these parameters from a HIV and AIDS patients enables to see pathogenesis a HIV infection and the prediction of its development from another side. |
| first_indexed | 2024-04-11T03:49:30Z |
| format | Article |
| id | doaj.art-2dd290dd4399477187747f83e8c10aae |
| institution | Directory Open Access Journal |
| issn | 2220-7619 2313-7398 |
| language | Russian |
| last_indexed | 2024-04-11T03:49:30Z |
| publishDate | 2014-06-01 |
| publisher | Sankt-Peterburg : NIIÈM imeni Pastera |
| record_format | Article |
| series | Инфекция и иммунитет |
| spelling | doaj.art-2dd290dd4399477187747f83e8c10aae2023-01-02T02:14:10ZrusSankt-Peterburg : NIIÈM imeni PasteraИнфекция и иммунитет2220-76192313-73982014-06-011211312010.15789/2220-7619-2011-2-113-12035OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2S. V. Khaidukov0A. V. Zurochka1Институт биоорганической химии им. акад. М.М. Шемякина и Ю.А. Овчинникова РАН, Москва ФГУ Федеральный Научно-Клинический Центр детской гематологии, онкологии и иммунологии РОСЗДРАВА, МоскваИнститут иммунологии и физиологии УрО РАН, г. ЕкатеринбургAbstract. Flow cytometry allows estimating quantitative and qualitative structure of populations and subpopulations of immune system cells by using various methodical approaches and a wide spectrum of reagents. For diagnostics the Acquired Immune Deficiency Syndrome (AIDS) caused by a Human Immunodeficiency Virus (HIV) the flow cytometry became irreplaceable. Traditionally, immunologists examine standard model of an estimation of immune dysfunction on the basis of classical markers of Т-cells (CD3, CD4, CD8) at the HIV-infection. But researchers pay less attention to other populations and subpopulations of lymphocytes, such as γδ-, αβ- and CD38+ Т-cells. The quantitative estimation of these parameters from a HIV and AIDS patients enables to see pathogenesis a HIV infection and the prediction of its development from another side.https://www.iimmun.ru/iimm/article/view/35flow cytometryaidscd38hivtcrγδ-t-cellsαβ-t-cells |
| spellingShingle | S. V. Khaidukov A. V. Zurochka OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2 Инфекция и иммунитет flow cytometry aids cd38 hiv tcr γδ-t-cells αβ-t-cells |
| title | OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2 |
| title_full | OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2 |
| title_fullStr | OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2 |
| title_full_unstemmed | OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2 |
| title_short | OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2 |
| title_sort | opportunities of flow cytometry in diagnostics of infectious diseases part 2 |
| topic | flow cytometry aids cd38 hiv tcr γδ-t-cells αβ-t-cells |
| url | https://www.iimmun.ru/iimm/article/view/35 |
| work_keys_str_mv | AT svkhaidukov opportunitiesofflowcytometryindiagnosticsofinfectiousdiseasespart2 AT avzurochka opportunitiesofflowcytometryindiagnosticsofinfectiousdiseasespart2 |