| Summary: | Olfactory neuroblastoma is a rare intranasal tumor, and the standard treatment for this disease remains controversial. Some clinicians contend that a combination of surgery and radiotherapy is the most efficacious approach, which frequently has a good prognosis. Chemotherapy is often reserved for those patients with tumor recurrence and distant metastasis. Regarding such metastasis, it is well-known that cervical metastasis indicates poor prognosis. We presented a 36-year-old woman who was diagnosed with a neuroblastoma with neck lymph node metastasis who did not undergo surgery. We treated her with chemotherapy followed by concurrent chemoradiation, and the result showed good response without sequela. We also reviewed the literature regarding the chemotherapy of olfactory neuroblastoma. In conclusion, olfactory neuroblastoma is highly sensitive to chemotherapy. However, long-term surveillanceof patients should be maintained in the event of local recurrence and distant metastasis.
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